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Anti-Pro-Insulin C-peptide Antibody (8G477) is a Mouse antibody targeting Pro-Insulin C-peptide. Anti-Pro-Insulin C-peptide Antibody (8G477) can be used in ELISA,ELISA(Det).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | $70 | 7-10 days | |
100 μL | $198 | 7-10 days |
Description | Anti-Pro-Insulin C-peptide Antibody (8G477) is a Mouse antibody targeting Pro-Insulin C-peptide. Anti-Pro-Insulin C-peptide Antibody (8G477) can be used in ELISA,ELISA(Det). |
Alias | PNDM4, MODY10, IRDN, ILPR, IDDM2, IDDM1, IDDM |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 8G477 |
Reactivity | Human |
Application | ELISA,ELISA(Det) |
Recommended Dose | ELISA: 1:1000-1:2000; ELISA(Det): 1:1000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with a synthetic peptide corresponding to the Human Pro-Insulin C-peptide. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. The binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Diseases associated with INS include Hyperproinsulinemia and Maturity-Onset Diabetes Of The Young, Type 10. A multitude of mutant alleles with phenotypic effects has been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes mellitus, maturity-onset diabetes of the young type 10, and hyperproinsulinemia.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide corresponding to the Human Pro-Insulin C-peptide |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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