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CPI1 is an effective and highly specific inhibitor of multidrug resistance protein 1 (MRP1). It exhibits inhibitory activity against MRP1 at the nanomolar level (Ki: 100 nM) and has minimal effect on P-glycoprotein (Pgp). CPI1 competes with LTC4 for binding to the same site on MRP1, inhibiting ATP hydrolysis and substrate transport. It is useful in research related to drug delivery and addressing cancer chemotherapy resistance.
Pack Size | Price | Availability | Quantity |
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10 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | CPI1 is an effective and highly specific inhibitor of multidrug resistance protein 1 (MRP1). It exhibits inhibitory activity against MRP1 at the nanomolar level (Ki: 100 nM) and has minimal effect on P-glycoprotein (Pgp). CPI1 competes with LTC4 for binding to the same site on MRP1, inhibiting ATP hydrolysis and substrate transport. It is useful in research related to drug delivery and addressing cancer chemotherapy resistance. |
Molecular Weight | 2299.43 |
Formula | C111H131N23O30S |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature. |
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