IL-13RA1 Protein, Human, Recombinant (His)

Name: IL-13RA1 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-01258
Price: 32 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: NR4, interleukin 13 receptor, α1, interleukin 13 receptor, alpha 1, IL-13Ra, CD213A1) Copy Product Info

Synonyms: NR4, interleukin 13 receptor, α1, interleukin 13 receptor, alpha 1, IL-13Ra, CD213A1

Catalog No. TMPY-01258 Copy Product Info

Purity: 98.6%

IL-13RA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P78552-1.

Pack Size	Price	USA Stock	Global Stock
10 µg	$32	-	In Stock
20 µg	$47	7-10 days	7-10 days
50 µg	$85	7-10 days	7-10 days
100 µg	$138	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Batch Information

Select Batch

Purity:98.6%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	1.Captured Human IL13RA1,His tag on NTA Chip can bind Human IL13 with an affinity constant of 10.20nM as determined in a SPR assay (Routinely tested) 2.Loaded Recombinant Human IL13RA1 Protein, His Tag on NTA Biosensor, can bind Recombinant Human IL-13 Protein with an affinity constant of 26.53 nM as determined in BLI assay (QC tested).
Description	IL-13RA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P78552-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	P78552-1
Construction	A DNA sequence encoding the human IL13Rα1 (NP_001551.1) extracellular domain (Met 1-Thr 343) expressed, with a C-terminal polyhistidine tag. Predicted N terminal: Gly 22
Protein Purity	> 97 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	NR4, interleukin 13 receptor, α1, interleukin 13 receptor, alpha 1, IL-13Ra, CD213A1
Research Background	Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. IL13RA1/IL-13RA1 serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2 and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3, and STAT6 induced by IL13 and IL4. IL13RA1/IL-13RA1 binds with low affinity to interleukin-13 (IL13). This subunit together with IL4RA can form a functional receptor for IL13. IL13RA1/IL-13RA1 also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.

Chemical Properties

Molecular Weight

38.3 kDa (predicted); 55-65 kDa (reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.