store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Apamin acetate (Apamine acetate) is a selective Ca2+-activated blocker of K+ (SK) channels, an 18-amino acid peptide neurotoxin found in bee toxins.Apamin acetate enhances synapse growth and regeneration following laceration injury to cortical neurons.Apamin acetate has anti-inflammatory and anti-fibrotic effects.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 183.00 | |
5 mg | In stock | $ 415.00 | |
10 mg | In stock | $ 597.00 | |
25 mg | In stock | $ 953.00 | |
50 mg | In stock | $ 1,290.00 | |
100 mg | In stock | $ 1,730.00 |
Description | Apamin acetate (Apamine acetate) is a selective Ca2+-activated blocker of K+ (SK) channels, an 18-amino acid peptide neurotoxin found in bee toxins.Apamin acetate enhances synapse growth and regeneration following laceration injury to cortical neurons.Apamin acetate has anti-inflammatory and anti-fibrotic effects. |
In vitro | Apamin acetate (0.5-2 µg/mL; 24 h; HSC-T6 cells) treatment effectively diminishes α-SMA expression in TGF-β1-induced HSC-T6 cells. Furthermore, Apamin acetate treatment prevents the activation of p-Smad2/3 and Smad4 induced by TGF-β1.[1] |
In vivo | Apamin acetate (0.1 mg/kg; i.p.; twice a week; for 4 weeks; C57BL/6 male mice) leads to reduced liver injury and lowered proinflammatory cytokine levels. Additionally, it inhibits collagen deposition, bile duct epithelial cell (BEC) proliferation, and the expression of fibrogenic genes in DDC-fed mice.[1] |
Synonyms | Apamine acetate, Apamin acetate(24345-16-2 Free base) |
Molecular Weight | N/A |
store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Apamin acetate Membrane transporter/Ion channel Potassium Channel Apamine acetate Apamine Acetate Apamin acetate(24345-16-2 Free base) Apamin Acetate inhibitor inhibit