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Anti-JNK1/2/MAPK10 Antibody (6S831)
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Catalog No. TMAC-02284
Alias Stress-activated protein kinase JNK3, Stress-activated protein kinase 1b, SAPK1b, SAPK1B, PRKM10, Mitogen-activated protein kinase 10, MAPK 10, MAP kinase p49 3F12, MAP kinase 10, JNK3A, JNK3, EC 2.7.11.24, c-Jun N-terminal kinase 3
Anti-JNK1/2/MAPK10 Antibody (6S831) is a Rabbit antibody targeting JNK1/2/MAPK10. Anti-JNK1/2/MAPK10 Antibody (6S831) can be used in ICC/IF,IP,WB.
Anti-JNK1/2/MAPK10 Antibody (6S831)
Anti-JNK1/2/MAPK10 Antibody (6S831)
😃Good
Catalog No. TMAC-02284Alias Stress-activated protein kinase JNK3, Stress-activated protein kinase 1b, SAPK1b, SAPK1B, PRKM10, Mitogen-activated protein kinase 10, MAPK 10, MAP kinase p49 3F12, MAP kinase 10, JNK3A, JNK3, EC 2.7.11.24, c-Jun N-terminal kinase 3
Anti-JNK1/2/MAPK10 Antibody (6S831) is a Rabbit antibody targeting JNK1/2/MAPK10. Anti-JNK1/2/MAPK10 Antibody (6S831) can be used in ICC/IF,IP,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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| Description | Anti-JNK1/2/MAPK10 Antibody (6S831) is a Rabbit antibody targeting JNK1/2/MAPK10. Anti-JNK1/2/MAPK10 Antibody (6S831) can be used in ICC/IF,IP,WB. |
| Synonyms | Stress-activated protein kinase JNK3, Stress-activated protein kinase 1b, SAPK1b, SAPK1B, PRKM10, Mitogen-activated protein kinase 10, MAPK 10, MAP kinase p49 3F12, MAP kinase 10, JNK3A, JNK3, EC 2.7.11.24, c-Jun N-terminal kinase 3 |
| Ig Type | IgG |
| Clone | 6S831 |
| Reactivity | Human,Mouse,Rat,Cow,Monkey,zebrafish |
| Verified Activity | 1. Western blot analysis of JNK1+JNK2+JNK3 on different cell lysates using anti-JNK1+JNK2+JNK3 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: PC12, Lane 3: K562, Lane 5: HepG2, Lane 6: Human lung. 2. Western blot analysis of JNK1+JNK2+JNK3 on hybrid fish (crucian-carp) brain tissue lysate using anti-JNK1+JNK2+JNK3 antibody at 1/500 dilution. 3. ICC staining JNK1+JNK2+JNK3 in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:1000-5000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | c-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield 10 isoforms through alternative mRNA splicing, including JNK1a1,JNK1b1, JNK2a1, JNK2b1, and JNK3a1, which represent the p46 isoforms, and JNK1a2, JNK1b2, JNK2a2, JNK2b2, and JNK3b2, which represent the p54 isoforms.JNKs coordinate cell responses to stress and influence regulation of cell growth and transformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun, and other signaling kinases, including MEKK1 and p38. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 46/54 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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