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Xenalipin

Name: Xenalipin
Brand: TargetMol
SKU: T19864
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T19864Cas No. 84392-17-6

Alias BW 207U

Xenalipin (BW 207U) has hypolipidemic. It reduces blood cholesterol and triglycerides in rats.

Xenalipin

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Purity: 99.78%

Catalog No. T19864Alias BW 207UCas No. 84392-17-6

Xenalipin (BW 207U) has hypolipidemic. It reduces blood cholesterol and triglycerides in rats.

Pack Size	Price	USA Warehouse	Global Warehouse
2 g	$30	-	In Stock
5 g	$51	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.78%

Appearance:solid

Color:White

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COA HNMR LCMS

Product Introduction

Xenalipin AI Summary

Xenalipin exhibits significant antiviral properties against multiple pathogens. It effectively inhibits the entry of Ebola virus with an AC50 of 0.7079 µM or 707.9 nM, demonstrating its promise in blocking viral entry. Additionally, the compound shows activity against SARS-CoV-2, inhibiting virus-induced cytotoxicity in Caco-2 cells by 6.1% at 10 µM over 48 hours and in VERO-6 cells by 0.25% under similar conditions. Furthermore, Xenalipin inhibits the SARS-CoV-2 3CL-Pro protease by -10.48% at 20 µM. Beyond its antiviral activity, the compound also exhibits moderate inhibitory activity on human HDAC6, achieving 9.73% inhibition with a commercial peptide substrate, though this decreases to -1.69% with a custom peptide substrate. These multifaceted inhibitory actions underscore its potential as a broad-spectrum antiviral agent..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Xenalipin (BW 207U) has hypolipidemic. It reduces blood cholesterol and triglycerides in rats.
Synonyms	BW 207U

Chemical Properties

Molecular Weight	266.22
Formula	C₁₄H₉F₃O₂
Cas No.	84392-17-6
Smiles	OC(=O)C1=C(C=CC=C1)C1=CC=C(C=C1)C(F)(F)F
Relative Density.	1.326 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (225.38 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 5 mg/mL (18.78 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7563 mL	18.7815 mL	37.5629 mL	187.8146 mL
5 mM	0.7513 mL	3.7563 mL	7.5126 mL	37.5629 mL
10 mM	0.3756 mL	1.8781 mL	3.7563 mL	18.7815 mL
20 mM	0.1878 mL	0.9391 mL	1.8781 mL	9.3907 mL
50 mM	0.0751 mL	0.3756 mL	0.7513 mL	3.7563 mL
100 mM	0.0376 mL	0.1878 mL	0.3756 mL	1.8781 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc