MMP-3 Protein, Human, Recombinant (His)

Name: MMP-3 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00447
Rating: 4.5 (1 reviews)

(Synonyms: Transin-1, Stromelysin-1, STMY1, SL-1, MMP-3, MMP3, Matrix metalloproteinase-3) Copy Product Info

Synonyms: Transin-1, Stromelysin-1, STMY1, SL-1, MMP-3, MMP3, Matrix metalloproteinase-3

Catalog No. TMPJ-00447 Copy Product Info

Purity: 97.3%

MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling.[3] The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.

Pack Size	Price	USA Stock	Global Stock
10 µg	$223	7-10 days	7-10 days
20 µg	$356	7-10 days	7-10 days
50 µg	$653	7-10 days	7-10 days
100 µg	$1,020	7-10 days	7-10 days
500 µg	$1,640	7-10 days	7-10 days
1 mg	$2,330	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:97.3%

Appearance:Solution

Color:Transparent

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling.[3] The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.
Species	Human
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	AAA36321.1
Amino Acid	Tyr18-Cys477
Construction	Tyr18-Cys477. The proenzyme needs to be activated by Chymotrypsin for an activated form.
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC. ,
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 10% Glycerol, pH 7.5.
Synonyms	Transin-1, Stromelysin-1, STMY1, SL-1, MMP-3, MMP3, Matrix metalloproteinase-3
Research Background	MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling.[3] The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.

Chemical Properties

Molecular Weight

50-65 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.