TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (hFc)

Name: TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPK-00708
Rating: 4.5 (1 reviews)

(Synonyms: TRAIL-R, TRAIL R1, TNFRSF10A, MGC9365, DR4, CD261, APO2) Copy Product Info

Synonyms: TRAIL-R, TRAIL R1, TNFRSF10A, MGC9365, DR4, CD261, APO2

Catalog No. TMPK-00708 Copy Product Info

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis selectively via its interaction with the death receptors TRAILR1/DR4 and TRAILR2/DR5 in a wide range of cancers, while sparing normal cells. Despite its tremendous potential for cancer therapeutics, the translation of TRAIL into the clinic has been confounded by TRAIL-resistant cancer populations.

TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (hFc)

Pack Size	Price	USA Stock	Global Stock
5 μg	$43	7-10 days	7-10 days
10 μg	$66	7-10 days	7-10 days
20 μg	$105	7-10 days	7-10 days
50 μg	$197	7-10 days	7-10 days
100 μg	$336	7-10 days	7-10 days
200 μg	$596	7-10 days	7-10 days
500 μg	$1,350	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity


Description	Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis selectively via its interaction with the death receptors TRAILR1/DR4 and TRAILR2/DR5 in a wide range of cancers, while sparing normal cells. Despite its tremendous potential for cancer therapeutics, the translation of TRAIL into the clinic has been confounded by TRAIL-resistant cancer populations.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	O00220
Construction	Pro34-Asn239
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Synonyms	TRAIL-R, TRAIL R1, TNFRSF10A, MGC9365, DR4, CD261, APO2
Research Background

Chemical Properties

Molecular Weight

48.8 kDa (predicted). Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Storage

Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

MGC-9365MGC 9365DR-4DR 4CD-261CD 261APO-2APO 2

Related Tags: TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (hFc) chemical structure | TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (hFc) molecular weight