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Aminooxy-PEG3-azide

Name: Aminooxy-PEG3-azide
Brand: TargetMol
SKU: T14264
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T14264Cas No. 1306615-51-9

Aminooxy-PEG3-azide is an ADC linker belonging to the class of PEGs, as well as three-unit PEGs, which can be used for the synthesis of antibody-coupled reactive molecules (ADCs).

Aminooxy-PEG3-azide

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Purity: 95.32%

Catalog No. T14264Cas No. 1306615-51-9

Aminooxy-PEG3-azide is an ADC linker belonging to the class of PEGs, as well as three-unit PEGs, which can be used for the synthesis of antibody-coupled reactive molecules (ADCs).

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$37	In Stock	In Stock
10 mg	$51	In Stock	In Stock
25 mg	$80	In Stock	In Stock
50 mg	$115	In Stock	In Stock
100 mg	$168	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:95.32%

Appearance:Liquid

Color:Transparent

Resource Download

COA GC HNMR

Product Introduction

Bioactivity

Description	Aminooxy-PEG3-azide is an ADC linker belonging to the class of PEGs, as well as three-unit PEGs, which can be used for the synthesis of antibody-coupled reactive molecules (ADCs).
In vitro	ADCs consist of an antibody linked to an ADC cytotoxin via an ADC linker[1]. PROTACs feature two ligands connected by a linker: one binds to an E3 ubiquitin ligase, and the other targets a specific protein. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].

Chemical Properties

Molecular Weight	234.25
Formula	C₈H₁₈N₄O₄
Cas No.	1306615-51-9
Smiles	[N-]=[N+]=NCCOCCOCCOCCON
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from direct sunlight,store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (1067.24 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.2689 mL	21.3447 mL	42.6894 mL	213.4472 mL
5 mM	0.8538 mL	4.2689 mL	8.5379 mL	42.6894 mL
10 mM	0.4269 mL	2.1345 mL	4.2689 mL	21.3447 mL
20 mM	0.2134 mL	1.0672 mL	2.1345 mL	10.6724 mL
50 mM	0.0854 mL	0.4269 mL	0.8538 mL	4.2689 mL
100 mM	0.0427 mL	0.2134 mL	0.4269 mL	2.1345 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc