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Anti-Jagged 1 Polyclonal Antibody
(Synonyms: JAGL1, Jagged 1, HJ1, CD339, AWS, AHD, AGS) Copy Product Info
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Synonyms: JAGL1, Jagged 1, HJ1, CD339, AWS, AHD, AGS
Catalog No. TMAB-01001 Copy Product Info
🥰Excellent
Anti-Jagged 1 Polyclonal Antibody is a Rabbit antibody targeting Jagged 1. Anti-Jagged 1 Polyclonal Antibody can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB.
Anti-Jagged 1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Jagged 1 Polyclonal Antibody is a Rabbit antibody targeting Jagged 1. Anti-Jagged 1 Polyclonal Antibody can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB. |
| Synonyms | JAGL1, Jagged 1, HJ1, CD339, AWS, AHD, AGS |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat) |
| Application | |
| Recommended Dose | ICC/IF=1:100-500; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane. |
| Tissue Specificity | Widely expressed in adult and fetal tissues. In cervix epithelium expressed in undifferentiated subcolumnar reserve cells and squamous metaplasia. Expression is up-regulated in cervical squamous cell carcinoma. Expressed in bone marrow cell line HS-27a wh |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq]. |
| Immunogen | KLH conjugated synthetic peptide: human CD339 |
| Antigen Species | Human |
| Gene Name | JAG1 |
| Gene ID | |
| Protein Name | Protein jagged-1 |
| Uniprot ID | |
| Biology Area | Inhibitors,Neurogenesis,Notch Pathway,Surface Molecules,Surface Molecules |
| Function | Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro). |
| Molecular Weight | Theoretical: 134 kDa. Actual: 22 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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