LSM4 Protein, Human, Recombinant (His)

Name: LSM4 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-01410
Rating: 4.5 (1 reviews)

(Synonyms: U6 snRNA-Associated Sm-Like Protein LSm4, LSM4, GRP, Glycine-Rich Protein) Copy Product Info

Synonyms: U6 snRNA-Associated Sm-Like Protein LSm4, LSM4, GRP, Glycine-Rich Protein

Catalog No. TMPJ-01410 Copy Product Info

U6 snRNA-associated Sm-like protein LSm4 (LSM4) is a member of the snRNP Sm proteins family. Sm-like proteins contain the Sm sequence motif and are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. LSM4 forms a heteromer with a donut shape. The complexes are involved in various steps of RNA metabolism. LSM4 binds specifically to the 3-terminal U-tract of U6 snRNA. LSM4 contributes RNA protein interactions and structural changes which are essential during ribosomal subunit assembly.

Pack Size	Price	USA Stock	Global Stock
5 µg	$112	35 days	35 days
10 µg	$183	35 days	35 days
20 µg	$292	35 days	35 days
50 µg	$545	35 days	35 days
100 µg	$792	35 days	35 days
200 µg	$1,150	35 days	35 days
500 µg	$1,900	35 days	35 days
1 mg	$2,730	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	U6 snRNA-associated Sm-like protein LSm4 (LSM4) is a member of the snRNP Sm proteins family. Sm-like proteins contain the Sm sequence motif and are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. LSM4 forms a heteromer with a donut shape. The complexes are involved in various steps of RNA metabolism. LSM4 binds specifically to the 3-terminal U-tract of U6 snRNA. LSM4 contributes RNA protein interactions and structural changes which are essential during ribosomal subunit assembly.
Species	Human
Expression System	E. coli
Tag	N-6xHis
Accession Number	Q9Y4Z0
Amino Acid	Met1-Gln139
Construction	Met1-Gln139
Protein Purity	Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 100 mM NaCl, 1 mM DTT, pH 8.0.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	U6 snRNA-Associated Sm-Like Protein LSm4, LSM4, GRP, Glycine-Rich Protein
Research Background	U6 snRNA-associated Sm-like protein LSm4 (LSM4) is a member of the snRNP Sm proteins family. Sm-like proteins contain the Sm sequence motif and are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. LSM4 forms a heteromer with a donut shape. The complexes are involved in various steps of RNA metabolism. LSM4 binds specifically to the 3-terminal U-tract of U6 snRNA. LSM4 contributes RNA protein interactions and structural changes which are essential during ribosomal subunit assembly.

Chemical Properties

Molecular Weight

17 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.