CXCL10 Protein, Human, Recombinant

Name: CXCL10 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPY-02970
Rating: 4.5 (1 reviews)

(Synonyms: SCYB10, mob-1, IP-10, INP10, IFI10, gIP-10, crg-2, chemokine (C-X-C motif) ligand 10, C7) Copy Product Info

Synonyms: SCYB10, mob-1, IP-10, INP10, IFI10, gIP-10, crg-2, chemokine (C-X-C motif) ligand 10, C7

Catalog No. TMPY-02970 Copy Product Info

CXCL10 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.8 kDa and the accession number is P02778.

Pack Size	Price	USA Stock	Global Stock
5 µg	$80	7-10 days	7-10 days
10 µg	$129	7-10 days	7-10 days
20 µg	$212	-	In Stock
50 µg	$359	7-10 days	7-10 days
100 µg	$539	7-10 days	7-10 days
200 µg	$945	7-10 days	7-10 days
500 µg	$1,990	7-10 days	7-10 days
1 mg	$3,520	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:89%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	CXCL10 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.8 kDa and the accession number is P02778.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	P02778
Construction	A DNA sequence encoding the mature form of human CXCL10 (NP_001556.2) (Val22-Pro98) was expressed, with a N-terminal Met. Predicted N terminal: Met
Protein Purity	> 90 % as determined by SDS-PAGE
Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	SCYB10, mob-1, IP-10, INP10, IFI10, gIP-10, crg-2, chemokine (C-X-C motif) ligand 10, C7
Research Background	(C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor coupled to G proteins. CXCL10/IP-10 and its receptor, CXCR3, appear to contribute to the pathogenesis of many autoimmune diseases, organ specific (such as type 1 diabetes, autoimmune thyroiditis, Graves' disease and ophthalmopathy), or systemic (such as rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, mixed cryoglobulinemia, Sjögren syndrome, or systemic sclerosis). CXCL10/IP-10 is secreted by several cell types including endothelial cells, fibroblasts, keratinocytes, thyrocytes, preadipocytes, etc. Determination of high level of CXCL10/IP-10 in peripheral fluids is therefore a marker of host immune response.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

Chemical Properties

Molecular Weight

8.8 kDa (predicted); 9 kDa (reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.