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Navamepent

Name: Navamepent
Brand: TargetMol
SKU: T71704
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T71704Cas No. 1251537-11-7

Alias RX-10045

Navamepent (RX-10045) is an analog of resolvin E1 (a dietary-3 polyunsaturated fatty acid metabolite), which has potent anti-inflammatory activity that reduces corneal inflammation, epithelial damage, and accelerates corneal tissue repair.Navamepent inhibits the release of several key pro-inflammatory mediators from corneal epithelial cells.Navamepent is very effective against dry eye and cupping cell loss Navamepent is effective against dry eye and cupping cell loss, and accelerates tear production.

Navamepent

😃Good

Purity: 99.03%

Catalog No. T71704Alias RX-10045Cas No. 1251537-11-7

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$322	Inquiry	Inquiry
5 mg	$753	Inquiry	Inquiry
10 mg	$1,230	Inquiry	Inquiry
25 mg	$1,960	Inquiry	Inquiry
50 mg	$2,830	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.03%

ee:97.72%

Appearance:Oil

Color:Yellow

Resource Download

COA CSFC HNMR LCMS

Product Introduction

Bioactivity

Description

Synonyms

RX-10045

Chemical Properties

Molecular Weight	304.38
Formula	C₁₈H₂₄O₄
Cas No.	1251537-11-7
Smiles	C(C[C@@H](C#C/C=C/C=C/[C@@H](CC#C)O)O)CC(OC(C)C)=O

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (164.27 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.57 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2854 mL	16.4268 mL	32.8537 mL	164.2683 mL
5 mM	0.6571 mL	3.2854 mL	6.5707 mL	32.8537 mL
10 mM	0.3285 mL	1.6427 mL	3.2854 mL	16.4268 mL
20 mM	0.1643 mL	0.8213 mL	1.6427 mL	8.2134 mL
50 mM	0.0657 mL	0.3285 mL	0.6571 mL	3.2854 mL
100 mM	0.0329 mL	0.1643 mL	0.3285 mL	1.6427 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc