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Anti-IL-2 R gamma/CD132 Antibody (6X102)

😃Good
Catalog No. TMAY-00965
Alias γC, SCIDX1, SCIDX, P64, IMD4, IL2RG, IL-2 R γ/CD132, IL-2 R γ, IL-2 R gamma, gammaC, CIDX, CD132

Anti-IL-2 R gamma/CD132 Antibody (6X102) is a Mouse antibody targeting IL-2 R gamma/CD132. Anti-IL-2 R gamma/CD132 Antibody (6X102) can be used in ELISA.

Anti-IL-2 R gamma/CD132 Antibody (6X102)

Anti-IL-2 R gamma/CD132 Antibody (6X102)

😃Good
Catalog No. TMAY-00965Alias γC, SCIDX1, SCIDX, P64, IMD4, IL2RG, IL-2 R γ/CD132, IL-2 R γ, IL-2 R gamma, gammaC, CIDX, CD132
Anti-IL-2 R gamma/CD132 Antibody (6X102) is a Mouse antibody targeting IL-2 R gamma/CD132. Anti-IL-2 R gamma/CD132 Antibody (6X102) can be used in ELISA.
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100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-IL-2 R gamma/CD132 Antibody (6X102) is a Mouse antibody targeting IL-2 R gamma/CD132. Anti-IL-2 R gamma/CD132 Antibody (6X102) can be used in ELISA.
AliasγC, SCIDX1, SCIDX, P64, IMD4, IL2RG, IL-2 R γ/CD132, IL-2 R γ, IL-2 R gamma, gammaC, CIDX, CD132
Ig Type
Monoclonal Mouse IgG2a
Clone
6X102
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD132 / IL2RG (rh CD132 / IL2RG; P31785)Met1-Asn254). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundThe common gamma chain (γc) (or CD132), also known as interleukin-2 receptor subunit gamma or IL2RG, is a member of the type I cytokine receptor family expressed on most lymphocyte (white blood cell) populations, and its gene is found on the X-chromosome of mammals. The common gamma chain (γc) (or IL2RG), is a cytokine receptor subunit that is common to the receptor complexes for at least six different interleukin receptors: IL-2, IL-4, IL-7, IL-9, IL-15, and the interleukin-21 receptor. It is a component of multiple cytokine receptors that are essential for lymphocyte development and function. X-linked severe combined immunodeficiency (X-SCID) is a rare and potentially fatal disease caused by mutations of IL2RG, the gene encoding IL2RG. IL2RG was demonstrated to be a component of the IL-4 receptor based on chemical cross-linking data, the ability of IL2RG to augment IL-4 binding affinity. The observation that IL-2R gamma is a functional component of the IL-4 receptor, together with the finding that IL-2R gamma associates with the IL-7 receptor, begins to elucidate why a deficiency of this common gamma chain (gamma c) has a profound effect on lymphoid function and development, as seen in X-linked severe combined immunodeficiency.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human CD132 / IL2RG Protein
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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