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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones Enzyme GPCR/G Protein Immunology / Inflammation JAK/STAT signaling
MAPK Membrane transporter/Ion channel Metabolism Microbiology&virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination Others
Compound Libraries Focused Bioactive Libraries Approved / Repurposing Characteristic Bioactive Libraries COVID-19 / SARS-CoV-2 Disease Focused Target / Pathway Focused Natural Product Libraries Characteristic Natural Product Libraries Natural Compound Library for HTS Fragment Libraries Diversity Sets Custom Compound Library
Signaling pathway Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones Enzyme GPCR/G Protein Immunology / Inflammation JAK/STAT signaling MAPK
Membrane transporter/Ion channel Metabolism Microbiology&virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling
Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination Others
Focused Bioactive Libraries Approved / Repurposing Characteristic Bioactive Libraries COVID-19 / SARS-CoV-2 Disease Focused Target / Pathway Focused
Natural Product Libraries Characteristic Natural Product Libraries Natural Compound Library for HTS Diversity Sets Golden Scaffold Library Mini Scaffold Library
Fragment Libraries Drug-fragment Library Featured Fragment Library High Solubility Fragment Library Custom Compound Library

Citations

(Literature published using targetmol products)
Nature 2019 May;569(7757):509-513.
Time-resolved protein activation by proximal decaging in living systems[J].
Nature 2019: 1-5.
Molecular architecture of lineage allocation and tissue organization in early mouse embryo[J].
Nature Medicine 2018 Dec;24(12):1919-1929.
Gut microbiota and intestinal FXR mediate the clinical benefits of metformin[J].
Nature Genetics 2018 Dec;50(12):1666-1673.
Cilia-driven cerebrospinal fluid flow directs expression of urotensin neuropeptides to straighten the vertebrate body axis[J].
Cancer Cell 2019 Jan 14;35(1):125-139.e9.
The ERBB-STAT3 axis drives Tasmanian devil facial tumor disease[J].
Cancer Cell 2019, 35(4): 677-691. e10.
Small-molecule targeting of oncogenic FTO demethylase in acute myeloid leukemia[J].
Immunity 2018 Apr 17;48(4):675-687.e7.
manganese Increases the Sensitivity of the cgas-sting Pathway for Double-stranded Dna and Is Required for the Host Defense against Dna Viruses[J].
Immunity 2018 Nov 20;49(5):842-856.e7.
Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages [J].
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