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Pyrrolnitrin
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Catalog No. T38413Cas No. 1018-71-9
Pyrrolnitrin, an antibiotic derived from Pseudomonas pyrrocinia, exhibits a broad spectrum of antibiotic activity, effectively targeting fungi, yeast, and gram-positive bacteria.
Pyrrolnitrin
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Catalog No. T38413Cas No. 1018-71-9
Pyrrolnitrin, an antibiotic derived from Pseudomonas pyrrocinia, exhibits a broad spectrum of antibiotic activity, effectively targeting fungi, yeast, and gram-positive bacteria.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 500 μg | $397 | 35 days | 35 days | |
| 1 mg | $778 | 35 days | 35 days | |
| 5 mg | $2,650 | 35 days | 35 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Pyrrolnitrin, an antibiotic derived from Pseudomonas pyrrocinia, exhibits a broad spectrum of antibiotic activity, effectively targeting fungi, yeast, and gram-positive bacteria. |
| In vitro | Pyrrolnitrin, at concentrations ranging from 0 to 100 μg/ml, demonstrates potent antibiotic properties against a diverse array of bacteria and fungi, exhibiting varying Minimum Inhibitory Concentration (MIC) values. Specifically, it is effective against Staphylococcus aureus, Mycobacterium, Bacillus subtillis, Candida albicans, Aspergillus niger, and Trichophyton rubrum, with respective MIC values of 50 μg/ml, 100 μg/ml, 0.78 μg/ml, 10 μg/ml, 12.5 μg/ml, and 1 μg/ml[1]. Additionally, when assessed in a microtitre plate assay, Pyrrolnitrin shows an antimicrobial effect against Arthrobacter oxydans ATCC 14358, Bacillus coagulans ATCC 7050, Bacillus licheniformis ATCC 14580, Bacillus subtilis ATCC 6051, and Bacillus thuringiensis ATCC 10792, all with an MIC of 6.25 μg/ml[2]. |
| Molecular Weight | 257.07 |
| Formula | C10H6Cl2N2O2 |
| Cas No. | 1018-71-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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