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Anti-PAFR/PAF Receptor Polyclonal Antibody

(Synonyms: RP23-470B20.1, Ptafr, Platelet-activating factor receptor, PAF-R, PAFR, PAF receptor, OTTMUSP00000010350, OTTHUMP00000004041) Copy Product Info
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Synonyms: RP23-470B20.1, Ptafr, Platelet-activating factor receptor, PAF-R, PAFR, PAF receptor, OTTMUSP00000010350, OTTHUMP00000004041

Catalog No. TMAB-01326 Copy Product Info
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Anti-PAFR/PAF Receptor Polyclonal Antibody is a Rabbit antibody targeting PAFR/PAF Receptor. Anti-PAFR/PAF Receptor Polyclonal Antibody can be used in FCM,IF,IHC-Fr,WB.
Anti-PAFR/PAF Receptor Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Anti-PAFR/PAF Receptor Polyclonal Antibody is a Rabbit antibody targeting PAFR/PAF Receptor. Anti-PAFR/PAF Receptor Polyclonal Antibody can be used in FCM,IF,IHC-Fr,WB.
SynonymsRP23-470B20.1, Ptafr, Platelet-activating factor receptor, PAF-R, PAFR, PAF receptor, OTTMUSP00000010350, OTTHUMP00000004041
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Chicken,Dog,Cow,Rabbit)
Application
Recommended Dose
WB: 1:500-2000; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1µg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein.
Tissue SpecificityExpressed in the placenta, lung, left and right heart ventricles, heart atrium, leukocytes and differentiated HL-60 granulocytes.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThe PAF receptor binds platelet-activating factor (PAF) and is thought to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. PAF is a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. It has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes. The PAF receptor is induced by granulocyte macrophage colony-stimulating factor (GM-CSF), interleukin-5 and n-butyrate. A diverse range of compounds act as PAF receptor antagonists; these may be useful pharmacologically.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PAFR
Antigen Species
Human
Gene Name
PTAFR
Gene ID
Protein Name
Platelet-activating factor receptor
Uniprot ID
Biology Area
Blood,Platelets,Macrophage / Inflamm.,GPCR
Function
Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system.
Chemical Properties
Molecular WeightTheoretical: 38 kDa. Actual: 38 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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