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Synonyms: RP23-470B20.1, Ptafr, Platelet-activating factor receptor, PAF-R, PAFR, PAF receptor, OTTMUSP00000010350, OTTHUMP00000004041
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
| Description | Anti-PAFR/PAF Receptor Polyclonal Antibody is a Rabbit antibody targeting PAFR/PAF Receptor. Anti-PAFR/PAF Receptor Polyclonal Antibody can be used in FCM,IF,IHC-Fr,WB. |
| Synonyms | RP23-470B20.1, Ptafr, Platelet-activating factor receptor, PAF-R, PAFR, PAF receptor, OTTMUSP00000010350, OTTHUMP00000004041 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Chicken,Dog,Cow,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1µg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Expressed in the placenta, lung, left and right heart ventricles, heart atrium, leukocytes and differentiated HL-60 granulocytes. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The PAF receptor binds platelet-activating factor (PAF) and is thought to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. PAF is a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. It has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes. The PAF receptor is induced by granulocyte macrophage colony-stimulating factor (GM-CSF), interleukin-5 and n-butyrate. A diverse range of compounds act as PAF receptor antagonists; these may be useful pharmacologically. |
| Immunogen | KLH conjugated synthetic peptide: human PAFR |
| Antigen Species | Human |
| Gene Name | PTAFR |
| Gene ID | |
| Protein Name | Platelet-activating factor receptor |
| Uniprot ID | |
| Biology Area | Blood,Platelets,Macrophage / Inflamm.,GPCR |
| Function | Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. |
| Molecular Weight | Theoretical: 38 kDa. Actual: 38 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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