Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-TOP2A Antibody (1C511)
😃Good
Catalog No. TMAH-01198
Alias TOP2, EC 5.99.1.3, DNA topoisomerase II, DNA topoisomerase 2-alpha, alpha isozyme
Anti-TOP2A Antibody (1C511) is an antibody targeting TOP2A. Anti-TOP2A Antibody (1C511) can be used in ELISA,IHC,WB.
Anti-TOP2A Antibody (1C511)
Anti-TOP2A Antibody (1C511)
😃Good
Catalog No. TMAH-01198Alias TOP2, EC 5.99.1.3, DNA topoisomerase II, DNA topoisomerase 2-alpha, alpha isozyme
Anti-TOP2A Antibody (1C511) is an antibody targeting TOP2A. Anti-TOP2A Antibody (1C511) can be used in ELISA,IHC,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $209 | 7-10 days | |
| 100 μL | $347 | 7-10 days |
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View MoreResource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-TOP2A Antibody (1C511) is an antibody targeting TOP2A. Anti-TOP2A Antibody (1C511) can be used in ELISA,IHC,WB. |
| Synonyms | TOP2, EC 5.99.1.3, DNA topoisomerase II, DNA topoisomerase 2-alpha, alpha isozyme |
| Ig Type | Rabbit IgG |
| Clone | 1C511 |
| Reactivity | Human, Mouse |
| Verified Activity | 1. Western Blot -Positive WB detected in: Hela whole cell lysate, Jurkat whole cell lysate, K562 whole cell lysate, NIH/3T3 whole cell lysate -All lanes: TOP2A antibody at 1:1500 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 175, 178, 179, 183 kDa -Observed band size: 175 kDa 2. IHC image of TMAH-01198 diluted at 1:100 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| Application | |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cytoplasm. Nucleus, nucleoplasm. Nucleus. Nucleus, nucleolus. |
| Tissue Specificity | Expressed in the tonsil, spleen, lymph node, thymus, skin, pancreas, testis, colon, kidney, liver, brain and lung. Also found in high-grade lymphomas, squamous cell lung tumors and seminomas. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human Topoisomerase II alpha |
| Antigen Species | Human |
| Gene Name | TOP2A |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Epigenetics and Nuclear Signaling, Cancer |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Sci Citations
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-TOP2A Antibody (1C511) | purchase Anti-TOP2A Antibody (1C511) | Anti-TOP2A Antibody (1C511) cost | order Anti-TOP2A Antibody (1C511)
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.