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AP-C2

🥰Excellent
Catalog No. T77570Cas No. 682793-07-3

AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.

AP-C2

AP-C2

🥰Excellent
Purity: 99.99%
Catalog No. T77570Cas No. 682793-07-3
AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$34-In Stock
5 mg$57-In Stock
10 mg$79-In Stock
25 mg$159-In Stock
50 mg$273-In Stock
100 mg$475-In Stock
200 mg$642-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.99%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.
Chemical Properties
Molecular Weight320.41
FormulaC18H16N4S
Cas No.682793-07-3
SmilesN1=CC=C(N=C1NCCC2=CNC=3C=CC=CC32)C=4SC=CC4
Relative Density.1.336 g/cm3 at 20℃ (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (140.45 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1210 mL15.6050 mL31.2100 mL156.0501 mL
5 mM0.6242 mL3.1210 mL6.2420 mL31.2100 mL
10 mM0.3121 mL1.5605 mL3.1210 mL15.6050 mL
20 mM0.1561 mL0.7803 mL1.5605 mL7.8025 mL
50 mM0.0624 mL0.3121 mL0.6242 mL3.1210 mL
100 mM0.0312 mL0.1561 mL0.3121 mL1.5605 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PKGAP-C2APC2
Related Tags: buy AP-C2 | purchase AP-C2 | AP-C2 cost | order AP-C2 | AP-C2 chemical structure | AP-C2 formula | AP-C2 molecular weight
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