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(RS)-APICA

🥰Excellent
Catalog No. T23268Cas No. 170847-18-4

group II metabotropic glutamate receptor antagonist

(RS)-APICA

(RS)-APICA

🥰Excellent
Catalog No. T23268Cas No. 170847-18-4
group II metabotropic glutamate receptor antagonist
TargetMol
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Product Introduction

Bioactivity
Description
group II metabotropic glutamate receptor antagonist
Chemical Properties
Molecular Weight257.18
FormulaC10H12NO5P
Cas No.170847-18-4
SmilesC(O)(=O)C1(N)C=2C(=CC(P(=O)(O)O)=CC2)CC1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
1.1eq. NaOH: 100 mM, Sonication is recommended.
Solution Preparation Table
1.1eq. NaOH
1mg5mg10mg50mg
1 mM3.8883 mL19.4416 mL38.8833 mL194.4164 mL
5 mM0.7777 mL3.8883 mL7.7767 mL38.8833 mL
10 mM0.3888 mL1.9442 mL3.8883 mL19.4416 mL
20 mM0.1944 mL0.9721 mL1.9442 mL9.7208 mL
50 mM0.0778 mL0.3888 mL0.7777 mL3.8883 mL
100 mM0.0389 mL0.1944 mL0.3888 mL1.9442 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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