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Anti-FADS2 Polyclonal Antibody

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Catalog No. TMAB-00651
Alias Fatty acid desaturase 2, FADS2, Delta(6) fatty acid desaturase (D6D;Delta(6) desaturase;Delta-6 desaturase), Acyl-CoA 6-desaturase

Anti-FADS2 Polyclonal Antibody is a Rabbit antibody targeting FADS2. Anti-FADS2 Polyclonal Antibody can be used in WB.

Anti-FADS2 Polyclonal Antibody

Anti-FADS2 Polyclonal Antibody

😃Good
Catalog No. TMAB-00651Alias Fatty acid desaturase 2, FADS2, Delta(6) fatty acid desaturase (D6D;Delta(6) desaturase;Delta-6 desaturase), Acyl-CoA 6-desaturase
Anti-FADS2 Polyclonal Antibody is a Rabbit antibody targeting FADS2. Anti-FADS2 Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2227-10 days
100 μL$3727-10 days
200 μL$5287-10 days
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Product Introduction

Bioactivity
Description
Anti-FADS2 Polyclonal Antibody is a Rabbit antibody targeting FADS2. Anti-FADS2 Polyclonal Antibody can be used in WB.
AliasFatty acid desaturase 2, FADS2, Delta(6) fatty acid desaturase (D6D;Delta(6) desaturase;Delta-6 desaturase), Acyl-CoA 6-desaturase
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Chicken,Pig,Cow,Horse,Rabbit)
Verified Activity
Sample:
Lane 1: Mouse Cerebrum tissue lysates
Lane 2: Mouse Heart tissue lysates
Primary: Anti-FADS2 (TMAB-00651) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52 kDa
Observed band size: 47 kDa
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationEndoplasmic reticulum membrane; Multi-pass membrane protein.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundMembers of the fatty acid desaturase (FADS) family, including FADS1, FADS2 and FADS3, regulate the desaturation of fatty acids by introducing double bonds between defined carbons of fatty acyl chains, thereby playing an essential role in the lipid metabolic pathway. Members of this family share N-terminal cytochrome b5-like domains, C-terminal multiple membrane-spanning desaturase regions and 3 histidine box motifs. FADS2 (fatty acid desaturase 2), also known as D6D, DES6, LLCDL2 or TU13, is a 444 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and contains one cytochrome b5 heme-binding domain. Expressed in adult and fetal heart and in adult liver, brain, lung and retina, FADS2 functions as a component of a lipid metabolic pathway and catalyzes the first step in the pathway, namely the formation of unsaturated fatty acids from polyunsaturated fatty acids. Defects in the gene encoding FADS2 are the cause of cause of fatty acid delta-6-desaturase deficiency, an affliction that is characterized by skin abnormalities, corneal ulceration and growth failure. Multiple isoforms of FADS2 exist due to alternative splicing events.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human FADS2
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
Metabolism,Fatty acids,Fatty acid oxidation,Metabolism,Lipid metabolism
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Keywords

δ-6 desaturaseδ6 desaturaseδ(6) fatty acid desaturase (D6D;δ(6) desaturase;δ-6 desaturase)FADS 2Delta-6 desaturaseDelta6 desaturased-6 desaturased6 desaturased(6) fatty acid desaturase (D6D;d(6) desaturase;d-6 desaturase)
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