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BDCA-2 Protein, Cynomolgus, Recombinant (mFc)

Catalog No. TMPK-00506
Synonyms: CLECSF11, BDCA2, DLEC, CLEC4C, CD303, HECL, BDCA-2, CLECSF7

BDCA-2 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with N-mFc tag. The predicted molecular weight is 46.00 kDa and the accession number is A0A2K5UWP4.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
BDCA-2 Protein, Cynomolgus, Recombinant (mFc)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 487.00
500 μg 5 days $ 1,950.00
1 mg 5 days $ 3,250.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description BDCA-2 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with N-mFc tag. The predicted molecular weight is 46.00 kDa and the accession number is A0A2K5UWP4.
Species Cynomolgus
Expression System HEK293 Cells
Tag N-mFc
Accession Number A0A2K5UWP4
Synonyms CLECSF11, BDCA2, DLEC, CLEC4C, CD303, HECL, BDCA-2, CLECSF7
Construction Tyr48-Ile212
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight 46.00 kDa (predicted). Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
Endotoxin < 1 EU/μg by the LAL method.
Formulation Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Stability & Storage

It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background BDCA-2, BDCA-3, and BDCA-4. In blood, BDCA-2 and BDCA-4 are expressed on CD11c(-) CD123(bright) plasmacytoid dendritic cells, whereas BDCA-3 is expressed on small population of CD11c() CD123(-) dendritic cells. All three Ags are not detectable on a third blood dendritic cell population, which is CD1c() CD11c(bright) CD123(dim), or on any other cells in blood.BDCA-2 is completely down-regulated on plasmacytoid CD11c(-) CD123(bright) dendritic cells, BDCA-2 is rapidly internalized at 37 degrees C after mAb labeling.

References and Literature

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Keywords

BDCA-2 Protein, Cynomolgus, Recombinant (mFc) CLECSF11 BDCA2 CLECSF 11 DLEC CLEC4C CLECSF 7 CD303 HECL BDCA-2 CD 303 CLECSF-11 CLECSF7 CLECSF-7 BDCA 2 CD-303 recombinant recombinant-proteins proteins protein

 

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