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Nectin-4 Protein IgV Domain, Human, Recombinant (His & Avi)

(Synonyms: PVRL4, PRR4, NECTIN4, LNIR, EDSS1) Copy Product Info

Synonyms: PVRL4, PRR4, NECTIN4, LNIR, EDSS1

Catalog No. TMPK-00309 Copy Product Info
Nectin-4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.(Microbial infection) Acts as a receptor for measles virus. Nectin-4 Protein IgV Domain, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 15.8 kDa and the accession number is Q96NY8-1.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$41-In Stock
10 μg$62-In Stock
20 μg$98-In Stock
50 μg$188-In Stock
100 μg$313In StockIn Stock
200 μg$5687-10 days7-10 days
500 μg$1,2607-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Immobilized Human Nectin-4 IgV Domain, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-Nectin-4 Antibody, hFc Tag with the EC50 of 16.8ng/ml determined by ELISA.
Description
Nectin-4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.(Microbial infection) Acts as a receptor for measles virus. Nectin-4 Protein IgV Domain, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 15.8 kDa and the accession number is Q96NY8-1.
Species
Human
Expression System
HEK293 Cells
TagC-His-Avi
Accession NumberQ96NY8-1
ConstructionGly32-Leu146
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsPVRL4, PRR4, NECTIN4, LNIR, EDSS1
Research Background
Chemical Properties
Molecular Weight15.8 kDa (predicted). Due to glycosylation, the protein migrates to 16-20 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: Nectin-4 Protein IgV Domain, Human, Recombinant (His & Avi) chemical structure | Nectin-4 Protein IgV Domain, Human, Recombinant (His & Avi) molecular weight