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Mupadolimab
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Catalog No. T76735Cas No. 2451856-97-4
Alias CPI-006
Mupadolimab (CPI-006) is a humanized FC-γR binding deficient IgG1 anti-CD73 antibody with potential anticancer activity and activation of CD73POS B cells.
Mupadolimab
Mupadolimab
😃Good
Catalog No. T76735Alias CPI-006Cas No. 2451856-97-4
Mupadolimab (CPI-006) is a humanized FC-γR binding deficient IgG1 anti-CD73 antibody with potential anticancer activity and activation of CD73POS B cells.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $222 | In Stock | In Stock | |
| 5 mg | $463 | In Stock | In Stock | |
| 10 mg | $878 | - | In Stock | |
| 25 mg | $1,280 | - | In Stock | |
| 50 mg | $1,760 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Mupadolimab (CPI-006) is a humanized FC-γR binding deficient IgG1 anti-CD73 antibody with potential anticancer activity and activation of CD73POS B cells. |
| In vitro | Mupadolimab induces increased expression of markers associated with B cell maturation and antigen presentation, transformation into plasma cells, as well as increased secretion of IgM and IgG[1]. |
| In vivo | Mupadolimab (10 mg/kg; intraperitoneal injection; once daily for 15 days) stimulates antigen-specific humoral immunity in NSG-SGM3 mice infected with SARS-CoV-2[1]. |
| Synonyms | CPI-006 |
| Reactivity | Human |
| Verified Activity | Immobilized Human NT5E Protein (ECD, His) at 2 μg/mL (30 μL/well) can bind Mupadolimab. The EC50 is 9.894 ng/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | NT5E/CD73 |
| Molecular Weight | 146.92 kDa |
| Cas No. | 2451856-97-4 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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