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Anti-CD83 Antibody-PE (1G44)
🥰Excellent
Catalog No. TMAY-02047P
Anti-CD83 Antibody-PE (1G44) is a PE-conjugated Mouse antibody targeting CD83. Anti-CD83 Antibody-PE (1G44) can be used in FCM.
Anti-CD83 Antibody-PE (1G44)
Anti-CD83 Antibody-PE (1G44)
🥰Excellent
Catalog No. TMAY-02047P
Anti-CD83 Antibody-PE (1G44) is a PE-conjugated Mouse antibody targeting CD83. Anti-CD83 Antibody-PE (1G44) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD83 Antibody-PE (1G44) is a PE-conjugated Mouse antibody targeting CD83. Anti-CD83 Antibody-PE (1G44) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG2b |
| Clone | 1G44 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human CD83 expression on DC. Cells were stained with PE-conjugated anti-Human CD83. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD83 (rh CD83; TMPY-01829; Q01151-1; Met1-Ala143) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD83 is considered as a marker of mature dendritic cells as well as an adhesion receptor that binds to resting monocytes and a subset of activated CD8+T cells. In certain conditions, CD83 tended to dimerize or even multimerize through its aberrant intermolecular disulfide bonds. The injection of CD83-Ig can significantly enhance the rate of tumor growth and inhibit the T cell growth. |
| Conjucates | PE |
| Others Formats | Unconjugated/FITC |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Human CD83 Protein (TMPY-01829) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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