Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-EPCR Antibody (8B109) is a Rabbit antibody targeting EPCR. Anti-EPCR Antibody (8B109) can be used in ELISA,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $269 | 7-10 days | 7-10 days |
| Description | Anti-EPCR Antibody (8B109) is a Rabbit antibody targeting EPCR. Anti-EPCR Antibody (8B109) can be used in ELISA,FCM. |
| Synonyms | protein C receptor, endothelial |
| Ig Type | Rabbit IgG |
| Clone | 8B109 |
| Reactivity | Mouse |
| Specificity | Mouse EPCR |
| Verified Activity | Flow cytometric analysis of Mouse PROCR(CD201) expression on bEnd.3 cells. Cells were stained with purified anti-Mouse PROCR(CD201), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000; FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Epcr / PROCR (rM Epcr / PROCR; TMPY-02487; Q64695; Met1-Ser214). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor) or PROCR, is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other animals after activated by binding to Endothelial protein C receptor (EPCR). Because of the EPCR is found primarily on endothelial cells (cells on the inside of blood vessels), activated protein C is found mainly near endothelial cells. Protein C is pleiotropic, with two main functions: anticoagulation and cytoprotection. Which function will be performed depending on whether or not protein C remains bind to EPCR after activated. The anticoagulation occurs when it does not. In this case, protein C functions as an anticoagulant by irreversibly proteolytically inactivating Factor Va and Factor VIIIa, turning them into Factor Vi and Factor VIIIi respectively. When still bound to EPCR, activated protein C performs its cytoprotective effects, acting on the effector substrate PAR-1, protease-activated receptor-1. To a degree, APC's anticoagulant properties are independent of its cytoprotective ones, in that expression of one pathway is not affected by the existence of the other. |
| Conjucates | Unconjugated |
| Others Formats | FITC |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Protein: Mouse Epcr / PROCR Protein (TMPY-02487) |
| Antigen Species | Mouse |
| Biology Area | Serine Proteases and Regulators |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
|---|

Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.