Powder: -20°C for 3 years | In solvent: -80°C for 1 year
14,15-Epoxyeicosatrienoic acid (14,15-EET), derived from Arachidonic acid metabolism, significantly inhibits platelet aggregation in vivo and enhances astrocytic Aβ clearance, making it relevant for Alzheimer's Disease research [1] [2].
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Description | 14,15-Epoxyeicosatrienoic acid (14,15-EET), derived from Arachidonic acid metabolism, significantly inhibits platelet aggregation in vivo and enhances astrocytic Aβ clearance, making it relevant for Alzheimer's Disease research [1] [2]. |
In vitro | 14,15-Epoxyeicosatrienoic acid (0-10 μM) promotes Aβ uptake in primary astrocyte cultures [1]. |
In vivo | 14,15-Epoxyeicosatrienoic acid (0.3 mg/kg i.v.) inhibits platelet aggregation in murine cerebral arterioles [2]. Meanwhile, administration of 14,15-Epoxyeicosatrienoic acid (200 ng/ml) into the hippocampus can reverse Aβ deposition in the brains of 6-month-old male FAD mice [1]. |
Synonyms | 14,15-EET |
Molecular Weight | 320.47 |
Formula | C20H32O3 |
CAS No. | 81276-03-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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14,15-Epoxyeicosatrienoic acid 81276-03-1 14,15-EET inhibitor inhibit