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Synonyms: Protease ICH-1, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, ICH1 NEDD2, EC 3.4.22.55, Caspase-2, Caspase2, CASP-2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
| Description | Anti-CASP2 Antibody (3Y15) is an antibody targeting CASP2. Anti-CASP2 Antibody (3Y15) can be used in ELISA,WB. |
| Synonyms | Protease ICH-1, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, ICH1 NEDD2, EC 3.4.22.55, Caspase-2, Caspase2, CASP-2 |
| Ig Type | Rabbit IgG |
| Clone | 3Y15 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB:1:500-1:5000. |
| Antibody Type | Monoclonal |
| Tissue Specificity | Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human Caspase-2 |
| Antigen Species | Human |
| Gene Name | CASP2 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cancer, Cell biology, Metabolism |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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