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Anti-CASP2 Antibody (3Y15) is an antibody targeting CASP2. Anti-CASP2 Antibody (3Y15) can be used in ELISA, WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $209 | 7-10 days | |
100 μL | $347 | 7-10 days |
Description | Antibody Type: Recombinant Monoclonal Application: ELISA, WB Reactivity: Human |
Alias | Protease ICH-1, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, ICH1 NEDD2, EC 3.4.22.55, Caspase-2, Caspase2, CASP-2 |
Ig Type | Rabbit IgG |
Clone | 3Y15 |
Reactivity | Human |
Verified Activity | Western Blot -Positive WB detected in: Hela whole cell lysate, Jurkat whole cell lysate, HL60 whole cell lysate, 293T whole cell lysate, K562 whole cell lysate -All lanes: CASP2 antibody at 1:2000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 51, 35, 11 kDa -Observed band size: 51 kDa |
Application | ELISA, WB |
Recommended Dose | WB:1:500-1:5000. |
Antibody Type | Monoclonal |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide: Human Caspase-2 |
Antigen Species | Human |
Gene ID | 835 |
Uniprot ID | |
Biology Area | Cancer, Cell biology, Metabolism |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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