TL1A/TNFSF15 Protein, Rat, Recombinant (hFc)

Name: TL1A/TNFSF15 Protein, Rat, Recombinant (hFc)
Brand: TargetMol
SKU: TMPY-03067
Rating: 4.5 (1 reviews)

(Synonyms: tumor necrosis factor (ligand) superfamily, member 15) Copy Product Info

Synonyms: tumor necrosis factor (ligand) superfamily, member 15

Catalog No. TMPY-03067 Copy Product Info

TL1A Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q8K3Y7.

TL1A/TNFSF15 Protein, Rat, Recombinant (hFc)

Pack Size	Price	USA Stock	Global Stock
5 µg	$63	7-10 days	7-10 days
10 µg	$98	7-10 days	7-10 days
20 µg	$163	7-10 days	7-10 days
50 µg	$323	7-10 days	7-10 days
100 µg	$625	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	TL1A Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q8K3Y7.
Species	Rat
Expression System	HEK293 Cells
Tag	N-hFc
Accession Number	Q8K3Y7
Construction	A DNA sequence encoding the rat TNFSF15 (Q8K3Y7) (Asp94-Ile252) was expressed, fused with the Fc region of human IgG1 at the N-terminus. Predicted N terminal: Asp 94
Protein Purity	> 90 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	tumor necrosis factor (ligand) superfamily, member 15
Research Background	TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon. TL1A is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It mediates activation of NF-kappa-B. It also inhibits vascular endothelial growth and angiogenesis (in vitro). TL1A promotes activation of caspases and apoptosis. It is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor.

Chemical Properties

Molecular Weight

46.5 kDa (predicted); 55 kDa (reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.