Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Azido-PEG3-chloroacetamide is a polyethylene glycol (PEG)-based linker. It serves as a crucial component in the synthesis of proteolysis-targeting chimeras (PROTACs), facilitating efficient conjugation between target protein-recruiting ligands and E3 ubiquitin ligase binders.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 mg | Inquiry | Inquiry | |
500 mg | Inquiry | Inquiry |
Description | Azido-PEG3-chloroacetamide is a polyethylene glycol (PEG)-based linker. It serves as a crucial component in the synthesis of proteolysis-targeting chimeras (PROTACs), facilitating efficient conjugation between target protein-recruiting ligands and E3 ubiquitin ligase binders. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Synonyms | Azido-PEG3-chloroacetamide |
Molecular Weight | 294.74 |
Formula | C10H19ClN4O4 |
CAS No. | 604766-23-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Azido-PEG3-chloroacetamide 604766-23-6 Azido-PEG-3-chloroacetamide AzidoPEG3chloroacetamide Azido PEG3 chloroacetamide inhibitor inhibit