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Anti-Phospho-Tau (Thr181) Polyclonal Antibody
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Catalog No. TMAB-01517
Anti-Phospho-Tau (Thr181) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Tau (Thr181). Anti-Phospho-Tau (Thr181) Polyclonal Antibody can be used in WB.
Anti-Phospho-Tau (Thr181) Polyclonal Antibody
Anti-Phospho-Tau (Thr181) Polyclonal Antibody
😃Good
Catalog No. TMAB-01517
Anti-Phospho-Tau (Thr181) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Tau (Thr181). Anti-Phospho-Tau (Thr181) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $373 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-Tau (Thr181) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Tau (Thr181). Anti-Phospho-Tau (Thr181) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Cow,Horse,Rabbit) |
| Verified Activity | 25 μg total protein per Lane of various lysates probed with phospho-Tau (Thr181) polyclonal antibody, unconjugated (TMAB-01517) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min. |
| Application | WB |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Note=Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system. |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human Tau around the phosphorylation site of Thr181 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Axon marker,Tangles & Tau,Neurodegenerative disease,Tau |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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