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SIRP gamma Protein, Human, Recombinant (hFc)
(Synonyms: SIRP-γ, SIRP-β-2, SIRP-Gamma, SIRPG, SIRP-Beta-2, SIRP-b2, SIRPB2, Signal-Regulatory Protein γ, Signal-Regulatory Protein Gamma, Signal-Fegulatory Protein β-2, Signal-Fegulatory Protein Beta-2, CD172g, CD172 Antigen-Like Family Member B) Copy Product InfoSynonyms: SIRP-γ, SIRP-β-2, SIRP-Gamma, SIRPG, SIRP-Beta-2, SIRP-b2, SIRPB2, Signal-Regulatory Protein γ, Signal-Regulatory Protein Gamma, Signal-Fegulatory Protein β-2, Signal-Fegulatory Protein Beta-2, CD172g, CD172 Antigen-Like Family Member B
Catalog No. TMPJ-00248 Copy Product Info
Signal-Regulatory Protein Gamma (SIRPG) is a member of the signal-regulatory protein (SIRP) family and also belongs to the immunoglobulin superfamily. SIRPG is detected in the liver, and at very low levels in the brain, heart, lung, pancreas, kidney, placenta, and skeletal muscle. SIRPG is an immunoglobulin-like cell surface receptor. On binding with CD47, SIRPG mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRPG as receptor-type transmembrane glycoproteins is involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $72 | 7-10 days | 7-10 days | |
| 10 μg | $116 | 7-10 days | 7-10 days | |
| 20 μg | $176 | 7-10 days | 7-10 days | |
| 50 μg | $310 | 7-10 days | 7-10 days | |
| 100 μg | $532 | 7-10 days | 7-10 days | |
| 200 μg | $919 | 7-10 days | 7-10 days | |
| 500 μg | $1,900 | 7-10 days | 7-10 days | |
| 1 mg | $2,730 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Signal-Regulatory Protein Gamma (SIRPG) is a member of the signal-regulatory protein (SIRP) family and also belongs to the immunoglobulin superfamily. SIRPG is detected in the liver, and at very low levels in the brain, heart, lung, pancreas, kidney, placenta, and skeletal muscle. SIRPG is an immunoglobulin-like cell surface receptor. On binding with CD47, SIRPG mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRPG as receptor-type transmembrane glycoproteins is involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | Q9P1W8 |
| Amino Acid | Glu29-Pro360 |
| Construction | Glu29-Pro360 |
| Protein Purity | Greater than 90% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | SIRP-γ, SIRP-β-2, SIRP-Gamma, SIRPG, SIRP-Beta-2, SIRP-b2, SIRPB2, Signal-Regulatory Protein γ, Signal-Regulatory Protein Gamma, Signal-Fegulatory Protein β-2, Signal-Fegulatory Protein Beta-2, CD172g, CD172 Antigen-Like Family Member B |
| Research Background |
| Molecular Weight | 80 KDa (reducing condition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: SIRP gamma Protein, Human, Recombinant (hFc) chemical structure | SIRP gamma Protein, Human, Recombinant (hFc) molecular weight
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