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Uridine-5'-diphosphate disodium salt

🥰Excellent
Catalog No. T4706Cas No. 27821-45-0
Alias UDP disodium salt

Uridine-5'-diphosphate disodium salt (UDP disodium salt) is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6), stimulating the production of inflammatory mediators, phagocytosis, and vasoconstriction. Uridine-5'-diphosphate disodium salt also acts as an antagonist of P2Y14.

Uridine-5'-diphosphate disodium salt

Uridine-5'-diphosphate disodium salt

🥰Excellent
Purity: 98.86%
Catalog No. T4706Alias UDP disodium saltCas No. 27821-45-0
Uridine-5'-diphosphate disodium salt (UDP disodium salt) is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6), stimulating the production of inflammatory mediators, phagocytosis, and vasoconstriction. Uridine-5'-diphosphate disodium salt also acts as an antagonist of P2Y14.
Pack SizePriceAvailabilityQuantity
50 mg$32In Stock
100 mg$45In Stock
500 mg$97In Stock
1 g$139In Stock
1 mL x 10 mM (in DMSO)$48In Stock
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Purity:98.86%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
Uridine-5'-diphosphate disodium salt (UDP disodium salt) is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6), stimulating the production of inflammatory mediators, phagocytosis, and vasoconstriction. Uridine-5'-diphosphate disodium salt also acts as an antagonist of P2Y14.
Targets&IC50
P2Y6 receptor:13 nM (EC50)
SynonymsUDP disodium salt
Chemical Properties
Molecular Weight448.12
FormulaC9H12N2Na2O12P2
Cas No.27821-45-0
SmilesO.[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP(O)([O-])=O)n1ccc(=O)[nH]c1=O
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 60 mg/mL (133.89 mM), Sonication is recommended.
H2O: 111 mg/mL (247.7 mM), Sonication and heating are recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM2.2315 mL11.1577 mL22.3155 mL111.5773 mL
5 mM0.4463 mL2.2315 mL4.4631 mL22.3155 mL
10 mM0.2232 mL1.1158 mL2.2315 mL11.1577 mL
20 mM0.1116 mL0.5579 mL1.1158 mL5.5789 mL
50 mM0.0446 mL0.2232 mL0.4463 mL2.2315 mL
100 mM0.0223 mL0.1116 mL0.2232 mL1.1158 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

Uridine5'diphosphate disodium saltUridine-5'-diphosphate disodiumUridine-5'-diphosphateUridine 5'-diphosphate disodium hydUridine 5' diphosphate disodium saltUDP disodiumUDPsubstratesRNASynthesisRNA SynthesisP2YReceptorP2Y6P2Y14P2Y ReceptorP2YnucleicglucuronidationEndogenousMetaboliteEndogenous MetaboliteDNASynthesisDNA/RNA SynthesisDNA Synthesis
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