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Antipyrine

Name: Antipyrine
Brand: TargetMol
SKU: T0734
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0734Cas No. 60-80-0

Alias Phenazone, Phenazon

Antipyrine (Phenazone), an antipyretic and analgesic, has been given as ear drops and by mouth. Antipyrine is frequently used to test the effects of other diseases or drugs on drug-metabolizing enzymes in the liver.

Antipyrine

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Purity: 99.77%

Catalog No. T0734Alias Phenazone, PhenazonCas No. 60-80-0

Pack Size	Price	USA Warehouse	Global Warehouse
1 g	$31	-	In Stock
5 g	$70	Inquiry	Inquiry
10 g	$98	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.77%

Appearance:Solid

Color:White

Resource Download

COA LCMS HPLC HNMR

Product Introduction

Bioactivity

Description	Antipyrine (Phenazone), an antipyretic and analgesic, has been given as ear drops and by mouth. Antipyrine is frequently used to test the effects of other diseases or drugs on drug-metabolizing enzymes in the liver.
In vitro	Antipyrine is an analgesic and antipyretic.
Synonyms	Phenazone, Phenazon

Chemical Properties

Molecular Weight	188.23
Formula	C₁₁H₁₂N₂O
Cas No.	60-80-0
Smiles	Cc1cc(=O)n(-c2ccccc2)n1C
Relative Density.	1.19 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 36 mg/mL (191.26 mM), Sonication is recommended.

H2O: 35 mg/mL (185.94 mM), Sonication is recommended.

DMSO: 110 mg/mL (584.39 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (21.25 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	5.3126 mL	26.5632 mL	53.1265 mL	265.6325 mL
5 mM	1.0625 mL	5.3126 mL	10.6253 mL	53.1265 mL
10 mM	0.5313 mL	2.6563 mL	5.3126 mL	26.5632 mL
20 mM	0.2656 mL	1.3282 mL	2.6563 mL	13.2816 mL
50 mM	0.1063 mL	0.5313 mL	1.0625 mL	5.3126 mL
100 mM	0.0531 mL	0.2656 mL	0.5313 mL	2.6563 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc