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Antipyrine

Name: Antipyrine
Brand: TargetMol
SKU: T0734
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0734Cas No. 60-80-0

Alias Phenazone, Phenazon

Antipyrine (Phenazone), an antipyretic and analgesic, has been given as ear drops and by mouth. Antipyrine is frequently used to test the effects of other diseases or drugs on drug-metabolizing enzymes in the liver.

Antipyrine

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Purity: 99.77%

Catalog No. T0734Alias Phenazone, PhenazonCas No. 60-80-0

Pack Size	Price	USA Warehouse	Global Warehouse
1 g	$31	-	In Stock
5 g	$70	-	In Stock
10 g	$98	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.77%

Resource Download

COA HPLC HNMR LCMS

Product Introduction

Bioactivity

Description	Antipyrine (Phenazone), an antipyretic and analgesic, has been given as ear drops and by mouth. Antipyrine is frequently used to test the effects of other diseases or drugs on drug-metabolizing enzymes in the liver.
In vitro	Antipyrine is an analgesic and antipyretic.
Synonyms	Phenazone, Phenazon

Chemical Properties

Molecular Weight	188.23
Formula	C₁₁H₁₂N₂O
Cas No.	60-80-0
Smiles	Cc1cc(=O)n(-c2ccccc2)n1C
Relative Density.	1.19 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 36 mg/mL (191.26 mM), Sonication is recommended.

H2O: 35 mg/mL (185.94 mM), Sonication is recommended.

DMSO: 110 mg/mL (584.39 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (21.25 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	5.3126 mL	26.5632 mL	53.1265 mL	265.6325 mL
5 mM	1.0625 mL	5.3126 mL	10.6253 mL	53.1265 mL
10 mM	0.5313 mL	2.6563 mL	5.3126 mL	26.5632 mL
20 mM	0.2656 mL	1.3282 mL	2.6563 mL	13.2816 mL
50 mM	0.1063 mL	0.5313 mL	1.0625 mL	5.3126 mL
100 mM	0.0531 mL	0.2656 mL	0.5313 mL	2.6563 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc