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Mycophenolic acid

Name: Mycophenolic acid
Brand: TargetMol
SKU: T1335
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1335Cas No. 24280-93-1

Alias RS-61443, Mycophenolate

Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.

Mycophenolic acid

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Purity: 99.77%

Catalog No. T1335Alias RS-61443, MycophenolateCas No. 24280-93-1

Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$40	In Stock	In Stock
100 mg	$48	In Stock	In Stock
500 mg	$81	In Stock	In Stock
1 g	$98	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.77%

Color:White

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Product Introduction

Bioactivity

Description	Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.
In vitro	In murine models, Mycophenolic acid selectively inhibits lymphocyte proliferation, cellular-mediated immune responses, and humoral immune responses.
In vivo	In cultured human, mouse, and rat T lymphocytes and B lymphocytes, Mycophenolic acid inhibits mitogen-induced proliferative responses. Mycophenolic acid can also induce apoptosis in activated CD4+ T cells.
Synonyms	RS-61443, Mycophenolate

Chemical Properties

Molecular Weight	320.34
Formula	C₁₇H₂₀O₆
Cas No.	24280-93-1
Smiles	CC1=C2C(=C(O)C(C/C=C(/CCC(O)=O)\C)=C1OC)C(=O)OC2
Relative Density.	1.29 g/cm3

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 125 mg/mL (390.21 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.24 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1217 mL	15.6084 mL	31.2168 mL	156.0842 mL
5 mM	0.6243 mL	3.1217 mL	6.2434 mL	31.2168 mL
10 mM	0.3122 mL	1.5608 mL	3.1217 mL	15.6084 mL
20 mM	0.1561 mL	0.7804 mL	1.5608 mL	7.8042 mL
50 mM	0.0624 mL	0.3122 mL	0.6243 mL	3.1217 mL
100 mM	0.0312 mL	0.1561 mL	0.3122 mL	1.5608 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc