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Dehydroandrographolide succinate potassium sodium salt
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Catalog No. T40971 Copy Product Info
Purity: 99.87%
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Dehydroandrographolide succinate potassium sodium salt is a natural product from Andrographis paniculata that exerts anti-inflammatory and immunomodulatory effects by inhibiting the production of inflammatory mediators (NO, TNF-α) and regulating immune responses. Dehydroandrographolide succinate exhibits antithrombotic effects. Dehydroandrographolide succinate can be used in research on viral pneumonia and viral upper respiratory tract infections.
Cas No. 863319-40-8
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 2 mg | $33 | - | In Stock | |
| 5 mg | $50 | - | In Stock | |
| 10 mg | $79 | - | In Stock | |
| 25 mg | $128 | - | In Stock | |
| 50 mg | $187 | - | In Stock | |
| 100 mg | $275 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.87%
Appearance:Solid
Color:Yellow
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Dehydroandrographolide succinate potassium sodium salt is a natural product from Andrographis paniculata that exerts anti-inflammatory and immunomodulatory effects by inhibiting the production of inflammatory mediators (NO, TNF-α) and regulating immune responses. Dehydroandrographolide succinate exhibits antithrombotic effects. Dehydroandrographolide succinate can be used in research on viral pneumonia and viral upper respiratory tract infections. |
| In vitro | Methods: Whole blood was collected from healthy volunteers. Dehydroandrographolide succinate potassium sodium salt was added to achieve final concentrations of 0.5, 1.0, and 1.5 mg/mL, and the samples were incubated at 37°C for 2 hours. A fully automated coagulation analyzer was used to measure prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (Fg), thrombin time (TT), and antithrombin III (AT-III) using an automated coagulation analyzer. [1] Results: Dehydroandrographolide succinate potassium sodium salt concentration-dependently shortened APTT and TT, increased fibrinogen (Fg) levels and antithrombin III (AT-III) activity; high-dose DAS significantly shortened PT and significantly enhanced anticoagulant capacity. |
| In vivo | Methods: Male SD rats were administered intraperitoneal injections of Dehydroandrographolide succinate potassium sodium salt at doses of 200, 400, and 600 mg/kg once daily for 3 consecutive days. Results: Dehydroandrographolide succinate potassium sodium salt (400, 600 mg/kg) significantly inhibited platelet aggregation, significantly shortened PT and APTT, and increased fibrinogen (Fg) levels and antithrombin III (AT-III) activity. [1] |
| Molecular Weight | 592.65 |
| Formula | C28H34KNaO10 |
| Cas No. | 863319-40-8 |
| Smiles | [H][C@]12CCC([C@H]([C@@]1(CC[C@H]([C@]2(COC(CCC([O-])=O)=O)C)OC(CCC([O-])=O)=O)C)/C=C/C3=CCOC3=O)=C.[Na+].[K+] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Related Tags: Dehydroandrographolide succinate potassium sodium salt chemical structure | Dehydroandrographolide succinate potassium sodium salt in vivo | Dehydroandrographolide succinate potassium sodium salt in vitro | Dehydroandrographolide succinate potassium sodium salt formula | Dehydroandrographolide succinate potassium sodium salt molecular weight
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