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n-acetylciprofloxacin
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Catalog No. T8606Cas No. 93594-20-8
Alias 3-Quinolinecarboxylic acid, 7-(4-acetyl-1-piperazinyl)-1-cyclopropyl-6-fluoro-1
n-acetylciprofloxacin (3-Quinolinecarboxylic acid, 7-(4-acetyl-1-piperazinyl)-1-cyclopropyl-6-fluoro-1) is inhibitor of H37Rv.
n-acetylciprofloxacin
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Purity: 99.83%
Catalog No. T8606Alias 3-Quinolinecarboxylic acid, 7-(4-acetyl-1-piperazinyl)-1-cyclopropyl-6-fluoro-1Cas No. 93594-20-8
n-acetylciprofloxacin (3-Quinolinecarboxylic acid, 7-(4-acetyl-1-piperazinyl)-1-cyclopropyl-6-fluoro-1) is inhibitor of H37Rv.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $80 | In Stock | In Stock | |
| 5 mg | $179 | In Stock | In Stock | |
| 10 mg | $272 | In Stock | In Stock | |
| 25 mg | $448 | In Stock | In Stock | |
| 50 mg | $630 | In Stock | In Stock | |
| 100 mg | $852 | In Stock | In Stock | |
| 200 mg | $1,130 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $197 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.83%
Appearance:Solid
Color:White
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Product Introduction
n-acetylciprofloxacin AI Summary
n-acetylciprofloxacin exhibits significant bioactivity, demonstrating antitumor, antimicrobial, and antibacterial properties. It shows antitumor activity against human cell lines, including PC3, U373MG, LoVo, A549, and MCF7, with IC50 values ranging from 323,000.0 nM to 803,000.0 nM after 5 days, as determined by MTT assay. This compound is a potent inhibitor of Human Jumonji Domain Containing 2E (JMJD2E) with a potency of 3162.3 nM and displays varied inhibitory and modulatory activities against several biological targets, such as Aldehyde Dehydrogenase 1 (ALDH1A1), Lipid Storage in Drosophila S3 Cells, and Histone Lysine Methyltransferase G9a. It also inhibits Mycobacterium tuberculosis H37Rv with an IC50 of 949.0 nM.
Additionally, n-acetylciprofloxacin exhibits antibacterial activity against multiple strains, including methicillin-resistant and methicillin-susceptible Staphylococcus aureus, Bacillus anthracis, Enterococcus faecalis, and Escherichia coli. The Minimum Inhibitory Concentration (MIC) against these strains, as determined by the CLSI method, is as low as 0.5 ug/mL for both Escherichia coli and Staphylococcus aureus, indicating strong microbial inhibition. The compound is noted for its broad-spectrum antimicrobial efficacy, particularly against challenging pathogens like methicillin-resistant Staphylococcus aureus (MRSA) and Bartonella species..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | n-acetylciprofloxacin (3-Quinolinecarboxylic acid, 7-(4-acetyl-1-piperazinyl)-1-cyclopropyl-6-fluoro-1) is inhibitor of H37Rv. |
| Synonyms | 3-Quinolinecarboxylic acid, 7-(4-acetyl-1-piperazinyl)-1-cyclopropyl-6-fluoro-1 |
| Molecular Weight | 373.38 |
| Formula | C19H20FN3O4 |
| Cas No. | 93594-20-8 |
| Smiles | CC(=O)N1CCN(CC1)C1=C(F)C=C2C(=O)C(=CN(C3CC3)C2=C1)C(O)=O |
| Relative Density. | 1.475 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | DMSO: 3.74 mg/mL (10.02 mM), Sonication is recommended.  H2O: Insoluble | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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