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Anti-METTL4 Polyclonal Antibody
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Catalog No. TMAB-01128
Alias snRNA (2'-O-methyladenosine-N(6)-)-methyltransferase METTL4, N(6)-adenine-specific methyltransferase METTL4, N(6)-adenine-specific DNA methyltransferase METTL4, METTL4, Methyltransferase-like protein 4
Anti-METTL4 Polyclonal Antibody is a Rabbit antibody targeting METTL4. Anti-METTL4 Polyclonal Antibody can be used in WB.
Anti-METTL4 Polyclonal Antibody
Anti-METTL4 Polyclonal Antibody
😃Good
Catalog No. TMAB-01128Alias snRNA (2'-O-methyladenosine-N(6)-)-methyltransferase METTL4, N(6)-adenine-specific methyltransferase METTL4, N(6)-adenine-specific DNA methyltransferase METTL4, METTL4, Methyltransferase-like protein 4
Anti-METTL4 Polyclonal Antibody is a Rabbit antibody targeting METTL4. Anti-METTL4 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-METTL4 Polyclonal Antibody is a Rabbit antibody targeting METTL4. Anti-METTL4 Polyclonal Antibody can be used in WB. |
| Synonyms | snRNA (2'-O-methyladenosine-N(6)-)-methyltransferase METTL4, N(6)-adenine-specific methyltransferase METTL4, N(6)-adenine-specific DNA methyltransferase METTL4, METTL4, Methyltransferase-like protein 4 |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Dog,Horse,Rabbit) |
| Verified Activity | 1. Sample: Liver (Rat) Cell Lysate at 40 μg Primary: Anti-METTL4 (TMAB-01128) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54 kDa Observed band size: 54 kDa 2. Sample: Lane 1: Mouse Heart tissue lysates Lane 2: Rat Cerebrum tissue lysates Primary: Anti-METTL4 (TMAB-01128) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54 kDa Observed band size: 54 kDa   |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | METTL4 is a 472 amino acid enzyme that belongs to the MT-A70-like family. Other members of this family have enzymatic activity that results in the transfer of a methyl group to and from DNA, RNA or amino acids. The gene encoding METTL4 maps to chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases, representing about 2.5% of total DNA in cells. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. Also, three chromosomal abnormalities result from meiotic nondisjunction events of chromosome 18: Monosomy 18p, Trisomy 18 (also known as Edwards syndrome) and Tetrasomy 18p. |
| Immunogen | KLH conjugated synthetic peptide: human METTL4 |
| Antigen Species | Human |
| Gene Name | METTL4 |
| Gene ID | |
| Protein Name | N(6)-adenine-specific methyltransferase METTL4 |
| Uniprot ID | |
| Biology Area | Methylated DNA,DNMTs,Methylated DNA Associated,Other Nuclear Bodies |
| Function | Probable methyltransferase. |
| Molecular Weight | Theoretical: 54 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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