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Anti-METTL4 Polyclonal Antibody

😃Good
Catalog No. TMAB-01128

Anti-METTL4 Polyclonal Antibody is a Rabbit antibody targeting METTL4. Anti-METTL4 Polyclonal Antibody can be used in WB.

Anti-METTL4 Polyclonal Antibody

Anti-METTL4 Polyclonal Antibody

😃Good
Catalog No. TMAB-01128
Anti-METTL4 Polyclonal Antibody is a Rabbit antibody targeting METTL4. Anti-METTL4 Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$221 7-10 days
100 μL$374 7-10 days
200 μL$528 7-10 days
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Product Introduction

Bioactivity
Description
Anti-METTL4 Polyclonal Antibody is a Rabbit antibody targeting METTL4. Anti-METTL4 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human,Dog,Horse,Rabbit)
Verified Activity
1. Sample:
Liver (Rat) Cell Lysate at 40 μg
Primary: Anti-METTL4 (TMAB-01128) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kDa
Observed band size: 54 kDa
2. Sample:
Lane 1: Mouse Heart tissue lysates
Lane 2: Rat Cerebrum tissue lysates
Primary: Anti-METTL4 (TMAB-01128) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kDa
Observed band size: 54 kDa
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundMETTL4 is a 472 amino acid enzyme that belongs to the MT-A70-like family. Other members of this family have enzymatic activity that results in the transfer of a methyl group to and from DNA, RNA or amino acids. The gene encoding METTL4 maps to chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases, representing about 2.5% of total DNA in cells. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. Also, three chromosomal abnormalities result from meiotic nondisjunction events of chromosome 18: Monosomy 18p, Trisomy 18 (also known as Edwards syndrome) and Tetrasomy 18p.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human METTL4
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
Methylated DNA,DNMTs,Methylated DNA Associated,Other Nuclear Bodies
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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