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Anti-METTL4 Polyclonal Antibody is a Rabbit antibody targeting METTL4. Anti-METTL4 Polyclonal Antibody can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $221 | 7-10 days | |
100 μL | $374 | 7-10 days | |
200 μL | $528 | 7-10 days |
Description | Anti-METTL4 Polyclonal Antibody is a Rabbit antibody targeting METTL4. Anti-METTL4 Polyclonal Antibody can be used in WB. |
Ig Type | IgG |
Reactivity | Mouse,Rat (predicted:Human,Dog,Horse,Rabbit) |
Verified Activity | 1. Sample: Liver (Rat) Cell Lysate at 40 μg Primary: Anti-METTL4 (TMAB-01128) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54 kDa Observed band size: 54 kDa 2. Sample: Lane 1: Mouse Heart tissue lysates Lane 2: Rat Cerebrum tissue lysates Primary: Anti-METTL4 (TMAB-01128) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54 kDa Observed band size: 54 kDa |
Application | WB |
Recommended Dose | WB: 1:500-2000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Hybridoma Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | METTL4 is a 472 amino acid enzyme that belongs to the MT-A70-like family. Other members of this family have enzymatic activity that results in the transfer of a methyl group to and from DNA, RNA or amino acids. The gene encoding METTL4 maps to chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases, representing about 2.5% of total DNA in cells. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. Also, three chromosomal abnormalities result from meiotic nondisjunction events of chromosome 18: Monosomy 18p, Trisomy 18 (also known as Edwards syndrome) and Tetrasomy 18p. |
Immunogen | KLH conjugated synthetic peptide: human METTL4 |
Antigen Species | Human |
Gene ID | |
Uniprot ID | |
Biology Area | Methylated DNA,DNMTs,Methylated DNA Associated,Other Nuclear Bodies |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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