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Anti-MAPK3/1 Antibody (1G244)

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Catalog No. TMAC-01371

Anti-MAPK3/1 Antibody (1G244) is a Rabbit antibody targeting MAPK3/1. Anti-MAPK3/1 Antibody (1G244) can be used in WB,ICC/IF,IP,FCM.

Anti-MAPK3/1 Antibody (1G244)

Anti-MAPK3/1 Antibody (1G244)

😃Good
Catalog No. TMAC-01371
Anti-MAPK3/1 Antibody (1G244) is a Rabbit antibody targeting MAPK3/1. Anti-MAPK3/1 Antibody (1G244) can be used in WB,ICC/IF,IP,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4967-10 days
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Product Introduction

Bioactivity
Description
Anti-MAPK3/1 Antibody (1G244) is a Rabbit antibody targeting MAPK3/1. Anti-MAPK3/1 Antibody (1G244) can be used in WB,ICC/IF,IP,FCM.
Ig Type
IgG
Reactivity
Human,Mouse,Rat,zebrafish
Application
Recommended Dose
WB: 1:1000-5000; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundMitogen-activated protein kinase (MAPK) signaling pathways involve two closely related MAP kinases, known as extracellular-signal-related kinase 1 (ERK 1, p44) and 2 (ERK 2, p42). Growth factors, steroid hormones, G protein-coupled receptor ligands and neurotransmitters can initiate MAPK signaling pathways. Activation of ERK 1 and ERK 2 requires phosphorylation by upstream kinases such as MAP kinasekinase (MEK), MEK kinase and Raf-1. ERK 1 and ERK 2 phosphorylation can occur at specific tyrosine and threonine sites mapping within consensus motifs that include the threonine-glutamate-tyrosine motif. ERK activation leads to dimerization with other ERKs and subsequent localization to the nucleus. Active ERK dimers phosphorylate serine and threonine residues on nuclear proteins and influence a host of responses that include proliferation, differentiation, transcription regulation and development. The human ERK 1 gene maps to chromosome 16p11.2 and encodes a 379 amino acid protein that shares 83% sequence identity to ERK 2. The human ERK2 gene maps to chromosome 22q11.21 and encodes a 360-amino acid protein.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 42/44 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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