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Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody

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Catalog No. TMAC-01731

Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody is a Rabbit antibody targeting Phospho-GSK3B (Tyr279, 216). Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody can be used in IF,WB,IHC,ELISA.

Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody

Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody

😃Good
Catalog No. TMAC-01731
Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody is a Rabbit antibody targeting Phospho-GSK3B (Tyr279, 216). Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody can be used in IF,WB,IHC,ELISA.
Pack SizePriceAvailabilityQuantity
50 μL$2167-10 days
100 μL$3177-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody is a Rabbit antibody targeting Phospho-GSK3B (Tyr279, 216). Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody can be used in IF,WB,IHC,ELISA.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundParticipates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of tyrosine 279/216 (V-S-Y(p)-I-C) derived from Human GSK3α/β
Antigen Species
human
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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