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Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody (Synonyms: p-HNRNPK (Ser216), p-HNRNPK (S216), HNRNPK (p-Ser2...)

Catalog No. TMAC-01995 Copy Product Info
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Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HNRNPK (Ser216). Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody can be used in WB.

Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-01995
Synonyms p-HNRNPK (Ser216), p-HNRNPK (S216), HNRNPK (p-Ser216), HNRNPK (p-S216)

Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HNRNPK (Ser216). Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody can be used in WB.

Anti-Phospho-HNRNPK
(Ser216) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2177-10 days7-10 days
100 μL$3177-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HNRNPK (Ser216). Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody can be used in WB.
Synonymsp-HNRNPK (Ser216), p-HNRNPK (S216), HNRNPK (p-Ser216), HNRNPK (p-S216)
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of extracts from JurKat cells, using hnRNP K (Phospho-Ser216) antibody TMAC-01995. The lane on the right is treated with the synthesized peptide.
verifiedActivity
Application
Recommended Dose
WB: 1:500-3000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundOne of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction By similarity. As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of serine 216 (S-E-S(p)-P-I) derived from Human hnRNP K
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 55 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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