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Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody
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Catalog No. TMAC-01995
Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HNRNPK (Ser216). Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody can be used in WB.
Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody
Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody
😃Good
Catalog No. TMAC-01995
Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HNRNPK (Ser216). Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $217 | 7-10 days | |
| 100 μL | $317 | 7-10 days |
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Chemical Properties
| Description | Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HNRNPK (Ser216). Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-3000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction By similarity. As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of serine 216 (S-E-S(p)-P-I) derived from Human hnRNP K |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 55 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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