ADAM8/CD156a Protein, Human, Recombinant (His)

Catalog No. TMPY-05532

ADAM8/CD156a Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is P78325.

ADAM8/CD156a Protein, Human, Recombinant (His)

Catalog No. TMPY-05532

ADAM8/CD156a Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is P78325.

Pack Size	Price	USA Warehouse	Global Warehouse
5 μg	$95	7-10 days	7-10 days
10 μg	$155	7-10 days	7-10 days
20 μg	$257	7-10 days	7-10 days
50 μg	$497	7-10 days	7-10 days
100 μg	$987	7-10 days	7-10 days
200 μg	$1,380	7-10 days	7-10 days
500 μg	$2,770	7-10 days	7-10 days
1 mg	$5,300	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse [1-2 days] Global Warehouse [5-7 days]

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Product Information

Biological Activity	Measured by its ability to cleave a fluorogenic peptide substrate Mca-PLAQAV-Dpa-RSSSR-NH2. The specific activity is >1 pmol/min/µg Immobilized Human ADAM8, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-ADAM8 Antibody, hFc Tag with the EC50 of 3.6 ng/ml determined by ELISA.
Description	ADAM8/CD156a Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is P78325.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	Q14C66
Synonyms	MS2,CD156a,CD156,ADAM metallopeptidase domain 8
Construction	A DNA sequence encoding the human ADAM8 (AAI15405.1) (Met1-Ser653) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Ile 17
Protein Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Molecular Weight	71 kDa (predicted); 55-70 kDa (Reducing conditions)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as sterile 12. 5 mM Tris, 5 mM CaCl2, 75 mM NaCl, 50% glycerol, pH 7.5.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Shipping with blue ice.
Research Background	A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer.