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Anti-SLAM/CD150 Antibody (2Q489)
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Catalog No. TMAY-01244
Alias signaling lymphocytic activation molecule family member 1
Anti-SLAM/CD150 Antibody (2Q489) is a Rabbit antibody targeting SLAM/CD150. Anti-SLAM/CD150 Antibody (2Q489) can be used in ELISA,IHC-P.
Anti-SLAM/CD150 Antibody (2Q489)
Anti-SLAM/CD150 Antibody (2Q489)
😃Good
Catalog No. TMAY-01244Alias signaling lymphocytic activation molecule family member 1
Anti-SLAM/CD150 Antibody (2Q489) is a Rabbit antibody targeting SLAM/CD150. Anti-SLAM/CD150 Antibody (2Q489) can be used in ELISA,IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $93 | 7-10 days | |
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA, IHC-P Reactivity: Human |
| Alias | signaling lymphocytic activation molecule family member 1 |
| Ig Type | Rabbit IgG |
| Clone | 2Q489 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human SLAMF1 in human tonsil with rabbit monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human SLAMF1 in human lymph node with rabbit monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections). 3. Immunochemical staining of human SLAMF1 in human appendix with rabbit monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections). |
| Application | ELISA,IHC-P |
| Recommended Dose | ELISA: 1:5000-1:10000; IHC-P: 1:1000-1:4000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human SLAMF1 / CD150 (rh SLAMF1; TMPY-01016; NP_003028.1; Met 1-Pro 258). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is expressed on thymocytes, activated and memory T cells, B cells, platelets, natural killer T cells, and mature dendritic cells, and is also detected on tumor cells of Hodgkin's lymphoma (HL) and diffuse large B-cell lymphoma with an activated B cell phenotype. Additionally, it is the immune cell receptor for measles virus (MV). As a self-ligand, CD150 performs diverse immunologic functions including T/B-cell costimulation, induction of interferon γ (IFN-γ) in Th1 T-cell clones, redirection of Th2 clones to a Th1 or Th0 phenotype, and inhibition of apoptosis in B cells. Furthermore, CD150 was shown to be the second receptor for measles virus in addition to CD46, and the distribution of SLAM on various cell lines is consistent with their susceptibility to clinical isolates of measles virus. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human CD150 protein (TMPY-01016) |
| Antigen Species | Human |
| Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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