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Anti-COMT Antibody (6P98)

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Catalog No. TMAH-00292
Alias HEL-S-98n, catechol-O-methyltransferase

Anti-COMT Antibody (6P98) is an antibody targeting COMT. Anti-COMT Antibody (6P98) can be used in ELISA, WB, IHC.

Anti-COMT Antibody (6P98)

Anti-COMT Antibody (6P98)

😃Good
Catalog No. TMAH-00292Alias HEL-S-98n, catechol-O-methyltransferase
Anti-COMT Antibody (6P98) is an antibody targeting COMT. Anti-COMT Antibody (6P98) can be used in ELISA, WB, IHC.
Pack SizePriceAvailabilityQuantity
50 μL$207 7-10 days
100 μL$347 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Rabbit Monoclonal

Application: ELISA, WB, IHC

Reactivity: Human
AliasHEL-S-98n, catechol-O-methyltransferase
Ig Type
Rabbit IgG
Clone
6P98
Reactivity
Human
Verified Activity
1. Western Blot
-Positive WB detected in: 293 whole cell lysate, THP-1 whole cell lysate, HepG2 whole cell lysate
-All lanes: COMT Antibody at 1:1000
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 31, 25 kDa
-Observed band size: 31 kDa
2. IHC image of TMAH-00292 diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
Application
ELISA, WB, IHC
Recommended Dose
WB:1:500-1:5000; IHC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular Localization[Isoform Soluble]: Cytoplasm.; [Isoform Membrane-bound]: Cell membrane; Single-pass type II membrane protein; Extracellular side.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundCatalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human COMT
Antigen Species
Human
Gene ID
1312
Uniprot ID
Biology Area
Neuroscience, Cancer, Metabolism, Signal transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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