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p-APMSF (hydrochloride)

Name: p-APMSF (hydrochloride)
Brand: TargetMol
SKU: T37019
Rating: 4.5 (1 reviews)

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Catalog No. T37019Cas No. 74938-88-8

p-APMSF is an irreversible inhibitor of serine proteases with Ki values of 1.02, 1.18, 1.5, and 1.54 μM for bovine trypsin, human thrombin, bovine plasmin, and bovine Factor Xa, respectively. It is selective for these proteases over bovine chymotrypsin and acetylcholinesterase.

p-APMSF (hydrochloride)

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Catalog No. T37019Cas No. 74938-88-8

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$120	35 days	35 days
5 mg	$323	35 days	35 days
10 mg	$568	35 days	35 days
25 mg	$1,290	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	252.69
Formula	C₈H₁₀ClFN₂O₂S
Cas No.	74938-88-8
Smiles	Cl.O=S(=O)(F)CC1=CC=C(C=C1)C(=N)N
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (197.87 mM), Sonication is recommended.

H2O: 25 mg/mL (98.94 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9574 mL	19.7871 mL	39.5742 mL	197.8709 mL
5 mM	0.7915 mL	3.9574 mL	7.9148 mL	39.5742 mL
10 mM	0.3957 mL	1.9787 mL	3.9574 mL	19.7871 mL
20 mM	0.1979 mL	0.9894 mL	1.9787 mL	9.8935 mL
50 mM	0.0791 mL	0.3957 mL	0.7915 mL	3.9574 mL

DMSO

	1mg	5mg	10mg	50mg
100 mM	0.0396 mL	0.1979 mL	0.3957 mL	1.9787 mL

Calculator

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Reconstitution Calculator
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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc