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Synonyms: activin A receptor, type IIB

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $85 | 7-10 days | 7-10 days | |
| 10 μg | $146 | 7-10 days | 7-10 days | |
| 20 μg | $242 | 7-10 days | 7-10 days | |
| 50 μg | $477 | 7-10 days | 7-10 days | |
| 100 μg | $929 | 7-10 days | 7-10 days |
| Bioactivity | Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 0.2-0.6 µg/mL in the presence of 10 ng/mL recombinant Activin A. |
| Description | ACVR2B Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.1 kDa and the accession number is G7MJ10. |
| Species | Cynomolgus |
| Expression System | HEK293 Cells |
| Tag | Tag Free |
| Accession Number | G7MJ10 |
| Construction | A DNA sequence encoding the cynomolgus ACVR2B (EHH16502.1) (Ser28-Thr143) was expressed with six amino acids (LEVLFQ) at the C-terminus. Predicted N terminal: Ser 28 |
| Protein Purity | > 95 % as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | activin A receptor, type IIB |
| Research Background |
| Molecular Weight | 14.1 kDa (predicted); 34 kDa (reducing conditions) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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