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Anti-MICB Antibody-PE (3I896)

🥰Excellent
Catalog No. TMAY-01131P

Anti-MICB Antibody-PE (3I896) is a PE-conjugated Mouse antibody targeting MICB. Anti-MICB Antibody-PE (3I896) can be used in FCM.

Anti-MICB Antibody-PE (3I896)

Anti-MICB Antibody-PE (3I896)

🥰Excellent
Catalog No. TMAY-01131P
Anti-MICB Antibody-PE (3I896) is a PE-conjugated Mouse antibody targeting MICB. Anti-MICB Antibody-PE (3I896) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-MICB Antibody-PE (3I896) is a PE-conjugated Mouse antibody targeting MICB. Anti-MICB Antibody-PE (3I896) can be used in FCM.
Ig Type
Monoclonal Mouse IgG1
Clone
3I896
Reactivity
Human
Verified Activity
Analysis of anti-MICB on HeLa cells.
Application
FCM
Recommended Dose
10 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MICB / MIC-B (rh MICB / MIC-B; TMPY-01066; NP_005922.2; Met 1-Gly 298) and conjugated with PE under optimum conditions, the unreacted PE was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundMHC class I polypeptide-related sequence B, also known as MICB, is a heavily glycosylated protein serving as a ligand for the type II receptor NKG2D. MICB shares 85% amino acid identity with MICA, a closely related protein, both of which contain three extracellular immunoglobulin-like domains, but without the capacity to bind peptide or interact with beta-2-microglobulin. acting as a stress-induced self-antigen, binding of MICB to the NKG2D receptor activates the cytolytic response of natural killer (NK) cells, CD8+αβ T cells, and γδ T cells on which the receptor is expressed. MICA/B is minimally expressed on normal cells, but are frequently expressed on epithelial tumors and can be induced by bacterial and viral infections. MICA/B recognition thus is involved in tumor surveillance, viral infections, and autoimmune diseases.
Related Conjugates and Formulations
Conjucates
PE
Others Formats
Unconjugated/APC/FITC
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Human MICB / MIC-B protein (TMPY-01066)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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