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Anti-L-selectin Antibody (9P769)
😃Good
Catalog No. TMAY-03058
Alias selectin L
Anti-L-selectin Antibody (9P769) is a Rabbit antibody targeting L-selectin. Anti-L-selectin Antibody (9P769) can be used in IHC-P.
Anti-L-selectin Antibody (9P769)
Anti-L-selectin Antibody (9P769)
😃Good
Catalog No. TMAY-03058Alias selectin L
Anti-L-selectin Antibody (9P769) is a Rabbit antibody targeting L-selectin. Anti-L-selectin Antibody (9P769) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-L-selectin Antibody (9P769) is a Rabbit antibody targeting L-selectin. Anti-L-selectin Antibody (9P769) can be used in IHC-P. |
| Alias | selectin L |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 9P769 |
| Reactivity | Mouse |
| Verified Activity | Immunochemical staining of mouse SELL in mouse spleen with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD62L / L-Selectin / SELL (rM CD62L / L-Selectin / SELL; TMPY-01184; NP_035476.1; Met1-Asn332). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | L-selectin (SELL), also known as CD62L, is a key adhesion molecule that regulates both the migration of leukocytes at sites of inflammation and the recirculation of lymphocytes between blood and lymphoid tissues. It belongs to the selectin family of proteins, and consisting of a large, highly glycosylated, extracellular domain, a single spanning transmembrane domain and a small cytoplasmic tail. L-selectin is the only selectin expressed on leukocytes and mediates a number of leukocyte-endothelial interactions. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point. L-selectin-mediated lymphocyte recirculation is required for maintaining the appropriate tissue distribution of lymphocyte subpopulations including naïve and effector subsets such as regulatory T cells. In addition, L-selectin-mediated entry into peripheral lymph nodes is required for optimal induction of lymphocyte homeostatic proliferation during lymphopenia. Importantly, L-selectin has been shown to have both adhesive and signaling functions during leukocyte migration. L-selectin has also been shown to mediate leukocyte recruitment during chronic inflammatory and autoimmune diseases and thus is a potential therapeutic target for drug development. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Mouse CD62L / L-Selectin / SELL Protein (TMPY-01184) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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