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Human herpesvirus 1 (HHV-1) (strain 17) ICP47 protein (His)
(Synonyms: Vmw12, US12 protein, US12, Infected cell protein 47, Immediate-early-5, Immediate-early protein IE12, ICP47 protein) Copy Product InfoSynonyms: Vmw12, US12 protein, US12, Infected cell protein 47, Immediate-early-5, Immediate-early protein IE12, ICP47 protein
Catalog No. TMPH-01444 Copy Product Info
Human herpesvirus 1 (HHV-1) (strain 17) ICP47 protein (His) is expressed in E. coli.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $129 | 20 days | 20 days | |
| 10 µg | $216 | 20 days | 20 days | |
| 20 µg | $360 | 20 days | 20 days | |
| 50 µg | $543 | 20 days | 20 days | |
| 100 µg | $745 | 20 days | 20 days | |
| 200 µg | $1,070 | 20 days | 20 days | |
| 500 µg | $1,730 | 20 days | 20 days | |
| 1 mg | $2,530 | 20 days | 20 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Human herpesvirus 1 (HHV-1) (strain 17) ICP47 protein (His) is expressed in E. coli. |
| Species | HHV-1 |
| Expression System | E. coli |
| Tag | N-10xHis |
| Accession Number | P03170 |
| Amino Acid | MSWALEMADTFLDTMRVGPRTYADVRDEINKRGREDREAARTAVHDPERPLLRSPGLLPEIAPNASLGVAHRRTGGTVTDSPRNPVTR |
| Construction | 1-88 aa |
| Protein Purity | > 85% as determined by SDS-PAGE. |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Tris-based buffer, 50% glycerol |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Synonyms | Vmw12, US12 protein, US12, Infected cell protein 47, Immediate-early-5, Immediate-early protein IE12, ICP47 protein |
| Research Background | Plays a role in the inhibition of host immune response. Binds specifically to transporters associated with antigen processing (TAP), thereby blocking peptide-binding and translocation by TAP as well as subsequent loading of peptides onto MHC class I molecules. Empty MHC I molecules are retained in the endoplasmic reticulum and ultimately directed to proteasomal degradation. In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes. |
| Molecular Weight | 13.3 kDa (predicted) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: Human herpesvirus 1 (HHV-1) (strain 17) ICP47 protein (His) chemical structure | Human herpesvirus 1 (HHV-1) (strain 17) ICP47 protein (His) molecular weight
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