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Anti-Phospho-RAF1 (Ser43) Antibody (1U306)

(Synonyms: RAF1 (p-Ser43), RAF1 (p-S43), p-RAF1 (Ser43), p-RAF1 (S43), Phospho-RAF1 (S43)) Copy Product Info
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Synonyms: RAF1 (p-Ser43), RAF1 (p-S43), p-RAF1 (Ser43), p-RAF1 (S43), Phospho-RAF1 (S43)

Catalog No. TMAC-03258 Copy Product Info
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Anti-Phospho-RAF1 (Ser43) Antibody (1U306) is a Rabbit antibody targeting Phospho-RAF1 (Ser43). Anti-Phospho-RAF1 (Ser43) Antibody (1U306) can be used in WB.
Anti-Phospho-RAF1
(Ser43) Antibody
(1U306)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-RAF1 (Ser43) Antibody (1U306) is a Rabbit antibody targeting Phospho-RAF1 (Ser43). Anti-Phospho-RAF1 (Ser43) Antibody (1U306) can be used in WB.
SynonymsRAF1 (p-Ser43), RAF1 (p-S43), p-RAF1 (Ser43), p-RAF1 (S43), Phospho-RAF1 (S43)
Ig Type
IgG
Clone
1U306
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundSeveral serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways. These include ERK/MAP kinases, ribosomal S6 kinase (Rsk)and Raf-1. Raf-1 is a cytoplasmic protein with intrinsic serine/threonine activity. It is broadly expressed in nearly all cell lines tested to date and is the cellular homolog of v-Raf, the product of the transforming gene of the 3611 strain of murine sarcoma virus. The unregulated kinase activity of the v-Raf protein has been associated with transformation and mitogenesis while the activity of Raf-1 is normally suppressed by a regulatory N-terminal domain. Raf-1 is activated in response to activation of a variety of tyrosine kinase receptors as well as in response to pp60v-Src expression. There is accumulating evidence that Ras p21 may play a role in activation of Raf-1 and may play the role of the messenger from membrane tyrosine kinases to Raf-1.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human Raf1 around the phosphorylation site of Ser43
Antigen Species
Human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 73 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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